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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
26.67
Human Site:
S456
Identified Species:
41.9
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S456
C
P
H
L
I
A
L
S
S
L
N
R
E
F
R
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S456
C
P
H
L
I
A
L
S
S
L
N
R
E
F
R
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
S456
C
P
H
L
I
A
L
S
L
N
R
E
F
R
P
Dog
Lupus familis
XP_536291
531
60932
S436
C
P
H
L
I
A
L
S
L
N
K
E
I
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
N454
L
I
A
L
S
S
V
N
R
E
F
R
P
F
R
Rat
Rattus norvegicus
NP_001009687
551
62702
S455
L
P
D
L
I
A
L
S
S
L
N
K
E
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
S532
C
P
D
L
V
D
L
S
A
F
N
K
E
F
S
Chicken
Gallus gallus
NP_001006581
551
63395
S457
C
P
D
L
V
D
L
S
T
L
H
K
T
L
K
Frog
Xenopus laevis
NP_001086801
548
62044
S453
Y
P
E
L
V
N
L
S
E
S
N
K
E
F
K
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
S419
C
P
D
L
V
D
L
S
A
C
N
K
E
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
V447
N
D
L
D
T
D
E
V
P
E
L
V
G
L
D
Honey Bee
Apis mellifera
XP_623367
426
49113
D336
E
E
C
K
E
N
V
D
E
E
N
S
I
N
D
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
E434
A
D
S
E
N
D
D
E
N
D
E
D
E
E
E
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
R401
G
A
S
N
K
Q
Y
R
P
H
R
S
E
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
P335
S
G
F
S
K
K
H
P
G
D
R
G
L
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
53.3
53.3
N.A.
26.6
80
N.A.
53.3
40
46.6
60
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
53.3
53.3
N.A.
46.6
86.6
N.A.
73.3
73.3
66.6
80
N.A.
0
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
34
0
0
14
0
0
0
0
7
0
% A
% Cys:
47
0
7
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
14
27
7
0
34
7
7
0
14
0
7
0
0
14
% D
% Glu:
7
7
7
7
7
0
7
7
14
20
7
14
54
14
7
% E
% Phe:
0
0
7
0
0
0
0
0
0
7
7
0
7
47
0
% F
% Gly:
7
7
0
0
0
0
0
0
7
0
0
7
7
0
0
% G
% His:
0
0
27
0
0
0
7
0
0
7
7
0
0
0
0
% H
% Ile:
0
7
0
0
34
0
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
0
7
14
7
0
0
0
0
7
34
0
0
14
% K
% Leu:
14
0
7
67
0
0
60
0
14
27
7
0
7
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
7
14
0
7
7
14
47
0
0
7
0
% N
% Pro:
0
60
0
0
0
0
0
7
14
0
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
7
0
20
20
0
7
34
% R
% Ser:
7
0
14
7
7
7
0
60
20
7
0
14
0
0
20
% S
% Thr:
0
0
0
0
7
0
0
0
7
0
0
0
7
7
7
% T
% Val:
0
0
0
0
27
0
14
7
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _