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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIOK2 All Species: 13.33
Human Site: S442 Identified Species: 20.95
UniProt: Q9BVS4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BVS4 NP_060813.2 552 63283 S442 Q G G V P A G S D E Y E D E C
Chimpanzee Pan troglodytes XP_517843 552 63335 S442 Q G G V P A G S D E Y E D E C
Rhesus Macaque Macaca mulatta XP_001095785 551 63384 S442 Q G G V P A G S E E Y D D E C
Dog Lupus familis XP_536291 531 60932 N422 Q G G M P M G N E E Y E D A C
Cat Felis silvestris
Mouse Mus musculus Q9CQS5 547 62472 C440 S P A G S E D C D D E P P H L
Rat Rattus norvegicus NP_001009687 551 62702 C441 G Q S S P A G C A E G E D E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512597 627 71085 S518 G R E A L A V S E E P E D E C
Chicken Gallus gallus NP_001006581 551 63395 K443 Q G D H C I D K D K E D D E C
Frog Xenopus laevis NP_001086801 548 62044 S439 G D D H D G D S D E C Q D E Y
Zebra Danio Brachydanio rerio NP_998719 512 58691 R405 G I S E D L G R D E V E D E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651365 538 61413 D433 A T N T V E E D V K S I S S N
Honey Bee Apis mellifera XP_623367 426 49113 I322 K E M G M I E I E D E E I E E
Nematode Worm Caenorhab. elegans NP_493544 529 60467 P420 Y K D I E L P P E D F K R P A
Sea Urchin Strong. purpuratus XP_784439 491 55586 D387 K E N H S D D D D D L E D I G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40160 425 49106 L321 D V K R T D N L D E L V Q A S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 81.6 N.A. 82.9 81.6 N.A. 62.5 65.5 67.2 67.3 N.A. 44.3 47.6 41.8 49.4
Protein Similarity: 100 99.6 98.7 88.5 N.A. 91.3 90 N.A. 72 79.1 80 77.9 N.A. 62.6 62.8 60.1 65
P-Site Identity: 100 100 86.6 66.6 N.A. 6.6 46.6 N.A. 46.6 40 33.3 46.6 N.A. 0 13.3 0 20
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 46.6 N.A. 53.3 53.3 40 46.6 N.A. 6.6 33.3 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 7 0 34 0 0 7 0 0 0 0 14 7 % A
% Cys: 0 0 0 0 7 0 0 14 0 0 7 0 0 0 47 % C
% Asp: 7 7 20 0 14 14 27 14 54 27 0 14 67 0 0 % D
% Glu: 0 14 7 7 7 14 14 0 34 60 20 54 0 60 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 27 34 27 14 0 7 40 0 0 0 7 0 0 0 7 % G
% His: 0 0 0 20 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 0 7 0 7 0 14 0 7 0 0 0 7 7 7 0 % I
% Lys: 14 7 7 0 0 0 0 7 0 14 0 7 0 0 0 % K
% Leu: 0 0 0 0 7 14 0 7 0 0 14 0 0 0 14 % L
% Met: 0 0 7 7 7 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 14 0 0 0 7 7 0 0 0 0 0 0 7 % N
% Pro: 0 7 0 0 34 0 7 7 0 0 7 7 7 7 0 % P
% Gln: 34 7 0 0 0 0 0 0 0 0 0 7 7 0 0 % Q
% Arg: 0 7 0 7 0 0 0 7 0 0 0 0 7 0 0 % R
% Ser: 7 0 14 7 14 0 0 34 0 0 7 0 7 7 7 % S
% Thr: 0 7 0 7 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 20 7 0 7 0 7 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 27 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _