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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK2
All Species:
20
Human Site:
S278
Identified Species:
31.43
UniProt:
Q9BVS4
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BVS4
NP_060813.2
552
63283
S278
D
F
F
M
K
R
F
S
Y
E
S
E
L
F
P
Chimpanzee
Pan troglodytes
XP_517843
552
63335
S278
D
F
F
M
K
R
F
S
Y
E
S
E
L
F
P
Rhesus Macaque
Macaca mulatta
XP_001095785
551
63384
S278
D
F
F
M
K
R
F
S
Y
E
S
E
L
F
P
Dog
Lupus familis
XP_536291
531
60932
S261
D
F
F
M
K
R
F
S
Y
E
S
E
L
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQS5
547
62472
S278
E
F
F
M
K
R
F
S
Y
E
S
E
L
Y
P
Rat
Rattus norvegicus
NP_001009687
551
62702
N278
E
F
F
L
K
R
F
N
Y
E
S
E
L
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512597
627
71085
N355
D
F
F
I
K
R
F
N
Y
E
S
E
L
Y
P
Chicken
Gallus gallus
NP_001006581
551
63395
N278
E
F
F
K
K
R
F
N
Y
E
S
E
L
F
P
Frog
Xenopus laevis
NP_001086801
548
62044
N278
D
F
F
L
R
R
F
N
Y
E
S
E
L
Y
P
Zebra Danio
Brachydanio rerio
NP_998719
512
58691
M250
T
M
I
D
F
P
Q
M
V
S
T
S
H
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651365
538
61413
G278
E
M
F
R
R
K
F
G
Y
E
S
E
D
Y
P
Honey Bee
Apis mellifera
XP_623367
426
49113
F169
Y
A
Y
M
K
A
L
F
D
R
G
F
P
V
P
Nematode Worm
Caenorhab. elegans
NP_493544
529
60467
Y261
D
H
P
N
A
E
Y
Y
F
D
R
D
V
T
C
Sea Urchin
Strong. purpuratus
XP_784439
491
55586
N234
M
V
S
T
S
H
E
N
A
E
W
Y
F
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40160
425
49106
M168
K
E
Y
Q
F
M
S
M
L
Y
S
K
G
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
81.6
N.A.
82.9
81.6
N.A.
62.5
65.5
67.2
67.3
N.A.
44.3
47.6
41.8
49.4
Protein Similarity:
100
99.6
98.7
88.5
N.A.
91.3
90
N.A.
72
79.1
80
77.9
N.A.
62.6
62.8
60.1
65
P-Site Identity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
80
80
73.3
0
N.A.
46.6
20
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
6.6
N.A.
73.3
26.6
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
7
0
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
47
0
0
7
0
0
0
0
7
7
0
7
7
0
0
% D
% Glu:
27
7
0
0
0
7
7
0
0
74
0
67
0
0
0
% E
% Phe:
0
60
67
0
14
0
67
7
7
0
0
7
7
34
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
7
0
7
0
0
% G
% His:
0
7
0
0
0
7
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
7
0
0
7
60
7
0
0
0
0
0
7
0
0
7
% K
% Leu:
0
0
0
14
0
0
7
0
7
0
0
0
60
0
0
% L
% Met:
7
14
0
40
0
7
0
14
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
34
0
0
0
0
0
7
7
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
0
0
7
0
74
% P
% Gln:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
14
60
0
0
0
7
7
0
0
0
7
% R
% Ser:
0
0
7
0
7
0
7
34
0
7
74
7
0
0
0
% S
% Thr:
7
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% T
% Val:
0
7
0
0
0
0
0
0
7
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
7
0
14
0
0
0
7
7
67
7
0
7
0
40
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _