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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM2
All Species:
20.61
Human Site:
Y290
Identified Species:
50.37
UniProt:
Q9BV94
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV94
NP_001138497.1
578
64753
Y290
Y
N
K
A
I
R
N
Y
T
R
F
D
D
W
Y
Chimpanzee
Pan troglodytes
XP_514601
578
64734
Y290
Y
N
K
A
I
R
N
Y
T
R
F
D
D
W
Y
Rhesus Macaque
Macaca mulatta
XP_001101476
578
64836
Y290
Y
N
K
A
I
R
N
Y
T
R
F
D
D
W
Y
Dog
Lupus familis
XP_534400
577
64681
Y290
Y
N
K
A
I
R
N
Y
T
R
F
D
D
W
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
F387
E
K
E
D
L
E
M
F
N
A
A
Y
Q
S
I
Rat
Rattus norvegicus
NP_001004230
576
64421
Y290
Y
N
K
A
I
R
N
Y
T
H
F
D
D
W
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQB9
913
102717
M309
N
T
H
Y
D
A
I
M
R
Y
I
S
Q
P
P
Zebra Danio
Brachydanio rerio
XP_696207
423
47287
D158
K
N
Y
T
K
F
D
D
W
Y
L
W
V
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122669
600
67917
Y285
H
K
A
A
I
E
K
Y
I
R
R
E
D
W
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
H327
N
V
M
A
D
T
G
H
L
F
V
P
W
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
96.1
N.A.
37.7
94.1
N.A.
N.A.
N.A.
26
54.6
N.A.
N.A.
53
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
98
N.A.
53.9
97.5
N.A.
N.A.
N.A.
37.9
65.7
N.A.
N.A.
68.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
93.3
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
N.A.
N.A.
0
13.3
N.A.
N.A.
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
70
0
10
0
0
0
10
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
20
0
10
10
0
0
0
50
60
0
10
% D
% Glu:
10
0
10
0
0
20
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
10
50
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
10
0
10
0
0
0
0
10
0
10
0
0
0
0
10
% H
% Ile:
0
0
0
0
60
0
10
0
10
0
10
0
0
10
10
% I
% Lys:
10
20
50
0
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% L
% Met:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
10
% M
% Asn:
20
60
0
0
0
0
50
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
20
10
0
% Q
% Arg:
0
0
0
0
0
50
0
0
10
50
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% S
% Thr:
0
10
0
10
0
10
0
0
50
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
10
10
60
0
% W
% Tyr:
50
0
10
10
0
0
0
60
0
20
0
10
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _