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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM2
All Species:
23.33
Human Site:
T64
Identified Species:
57.04
UniProt:
Q9BV94
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV94
NP_001138497.1
578
64753
T64
F
D
E
L
R
P
L
T
C
D
G
H
D
T
W
Chimpanzee
Pan troglodytes
XP_514601
578
64734
T64
F
D
E
L
R
P
L
T
C
D
G
H
D
T
W
Rhesus Macaque
Macaca mulatta
XP_001101476
578
64836
T64
F
D
E
L
R
P
L
T
C
D
G
H
D
T
W
Dog
Lupus familis
XP_534400
577
64681
T64
Y
D
E
L
R
P
L
T
C
D
G
H
D
T
W
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
N167
P
D
R
G
D
P
S
N
L
N
I
N
D
V
L
Rat
Rattus norvegicus
NP_001004230
576
64421
T64
Y
D
E
L
R
P
L
T
C
D
G
H
D
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQB9
913
102717
R79
I
R
G
Q
E
P
S
R
G
D
V
D
D
A
L
Zebra Danio
Brachydanio rerio
XP_696207
423
47287
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122669
600
67917
S59
Y
D
E
L
R
S
L
S
C
D
G
F
D
T
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
T80
E
D
P
T
D
Q
G
T
N
D
I
L
G
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
96.1
N.A.
37.7
94.1
N.A.
N.A.
N.A.
26
54.6
N.A.
N.A.
53
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
98
N.A.
53.9
97.5
N.A.
N.A.
N.A.
37.9
65.7
N.A.
N.A.
68.5
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
20
93.3
N.A.
N.A.
N.A.
20
0
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
N.A.
N.A.
20
0
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% C
% Asp:
0
80
0
0
20
0
0
0
0
80
0
10
80
0
0
% D
% Glu:
10
0
60
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
30
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
0
10
10
0
0
10
0
10
0
60
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
60
0
0
60
0
10
0
0
10
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
0
10
0
10
0
% N
% Pro:
10
0
10
0
0
70
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
10
0
60
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
20
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
60
0
0
0
0
0
60
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% W
% Tyr:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _