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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDEM2
All Species:
23.33
Human Site:
S230
Identified Species:
57.04
UniProt:
Q9BV94
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV94
NP_001138497.1
578
64753
S230
M
R
L
W
E
S
R
S
D
I
G
L
V
G
N
Chimpanzee
Pan troglodytes
XP_514601
578
64734
S230
M
R
L
W
E
S
R
S
D
I
G
L
V
G
N
Rhesus Macaque
Macaca mulatta
XP_001101476
578
64836
S230
M
R
L
W
E
S
R
S
D
I
G
L
V
G
N
Dog
Lupus familis
XP_534400
577
64681
S230
M
R
L
W
E
S
R
S
D
I
G
L
V
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q925U4
652
73682
W332
R
R
A
V
K
A
L
W
N
L
R
S
N
D
T
Rat
Rattus norvegicus
NP_001004230
576
64421
S230
M
R
L
W
E
S
R
S
D
I
G
L
V
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQB9
913
102717
R251
F
L
W
D
K
R
Q
R
S
S
N
L
V
G
V
Zebra Danio
Brachydanio rerio
XP_696207
423
47287
V104
L
V
G
N
H
I
D
V
I
T
S
K
W
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122669
600
67917
S225
K
A
L
H
Y
Y
K
S
N
I
G
L
V
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38888
796
91227
T251
D
K
T
W
S
L
R
T
G
L
D
L
L
P
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
96.1
N.A.
37.7
94.1
N.A.
N.A.
N.A.
26
54.6
N.A.
N.A.
53
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
98
N.A.
53.9
97.5
N.A.
N.A.
N.A.
37.9
65.7
N.A.
N.A.
68.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
N.A.
N.A.
20
0
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
N.A.
N.A.
33.3
6.6
N.A.
N.A.
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
0
50
0
10
0
0
10
0
% D
% Glu:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
60
0
0
70
0
% G
% His:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
60
0
0
0
0
0
% I
% Lys:
10
10
0
0
20
0
10
0
0
0
0
10
0
0
0
% K
% Leu:
10
10
60
0
0
10
10
0
0
20
0
80
10
0
0
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
20
0
10
0
10
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
10
60
0
0
0
10
60
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
50
0
60
10
10
10
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
10
% T
% Val:
0
10
0
10
0
0
0
10
0
0
0
0
70
10
10
% V
% Trp:
0
0
10
60
0
0
0
10
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _