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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THUMPD3
All Species:
22.42
Human Site:
S378
Identified Species:
44.85
UniProt:
Q9BV44
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV44
NP_001107564.1
507
57003
S378
Q
I
K
E
G
K
P
S
W
G
L
P
I
D
A
Chimpanzee
Pan troglodytes
XP_516257
507
57028
S378
Q
I
K
E
G
K
P
S
W
G
L
P
I
D
A
Rhesus Macaque
Macaca mulatta
XP_001096880
503
56618
S378
K
L
K
K
G
K
T
S
W
G
L
P
I
D
A
Dog
Lupus familis
XP_852757
680
75250
S556
Q
I
K
E
G
K
V
S
W
G
L
P
I
D
A
Cat
Felis silvestris
Mouse
Mus musculus
P97770
505
56413
T380
Q
I
K
D
G
K
T
T
W
G
L
P
I
D
A
Rat
Rattus norvegicus
NP_001164017
504
56364
S379
Q
I
K
D
G
K
T
S
W
G
L
P
I
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234566
472
52589
N348
S
L
L
K
K
N
E
N
K
E
S
S
A
S
L
Frog
Xenopus laevis
NP_001086861
469
52022
S345
E
S
I
D
A
V
I
S
D
I
P
F
G
R
K
Zebra Danio
Brachydanio rerio
NP_001082863
477
53218
L353
V
Q
W
D
L
C
N
L
P
M
R
S
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394352
414
47587
C290
I
E
A
S
S
S
K
C
K
I
D
L
L
H
W
Nematode Worm
Caenorhab. elegans
NP_502174
391
44053
M267
L
G
G
D
N
H
E
M
A
M
S
R
C
L
Q
Sea Urchin
Strong. purpuratus
XP_001194807
468
52831
D344
P
L
K
S
S
S
V
D
V
F
V
T
D
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
63.6
N.A.
80
79.8
N.A.
N.A.
63.1
21.1
56.4
N.A.
N.A.
34.3
31.9
37.4
Protein Similarity:
100
99.8
98
68.8
N.A.
88.5
88.3
N.A.
N.A.
75.3
39.8
71.9
N.A.
N.A.
50.4
45.7
55
P-Site Identity:
100
100
73.3
93.3
N.A.
80
86.6
N.A.
N.A.
0
6.6
0
N.A.
N.A.
0
0
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
20
6.6
N.A.
N.A.
6.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
9
0
0
0
9
0
50
% A
% Cys:
0
0
0
0
0
9
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
42
0
0
0
9
9
0
9
0
9
50
0
% D
% Glu:
9
9
0
25
0
0
17
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
0
9
9
0
50
0
0
0
0
50
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
42
9
0
0
0
9
0
0
17
0
0
50
0
0
% I
% Lys:
9
0
59
17
9
50
9
0
17
0
0
0
0
0
9
% K
% Leu:
9
25
9
0
9
0
0
9
0
0
50
9
9
17
9
% L
% Met:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
9
9
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
17
0
9
0
9
50
0
0
9
% P
% Gln:
42
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% R
% Ser:
9
9
0
17
17
17
0
50
0
0
17
17
9
17
0
% S
% Thr:
0
0
0
0
0
0
25
9
0
0
0
9
0
0
0
% T
% Val:
9
0
0
0
0
9
17
0
9
0
9
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
50
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _