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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THUMPD3
All Species:
15.45
Human Site:
S177
Identified Species:
30.91
UniProt:
Q9BV44
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV44
NP_001107564.1
507
57003
S177
N
V
K
K
E
F
T
S
H
A
L
D
S
H
I
Chimpanzee
Pan troglodytes
XP_516257
507
57028
S177
N
V
K
K
E
F
T
S
H
A
L
D
S
H
I
Rhesus Macaque
Macaca mulatta
XP_001096880
503
56618
S177
N
V
K
K
E
F
T
S
H
A
L
D
S
H
I
Dog
Lupus familis
XP_852757
680
75250
N355
D
D
K
K
G
F
I
N
N
T
L
D
S
H
I
Cat
Felis silvestris
Mouse
Mus musculus
P97770
505
56413
S179
D
G
K
K
K
H
A
S
S
T
S
D
S
H
I
Rat
Rattus norvegicus
NP_001164017
504
56364
S178
D
G
K
K
K
L
A
S
G
A
A
D
P
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234566
472
52589
S162
R
A
M
Q
G
E
A
S
Q
N
E
E
D
D
N
Frog
Xenopus laevis
NP_001086861
469
52022
L159
N
T
M
D
S
K
E
L
D
A
T
E
Q
Q
L
Zebra Danio
Brachydanio rerio
NP_001082863
477
53218
N167
D
V
S
P
N
L
E
N
D
S
E
E
D
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394352
414
47587
P104
G
F
Q
G
K
I
Y
P
T
T
D
E
Y
N
L
Nematode Worm
Caenorhab. elegans
NP_502174
391
44053
L81
E
M
Q
K
E
D
A
L
K
T
I
Q
S
Q
I
Sea Urchin
Strong. purpuratus
XP_001194807
468
52831
V158
S
D
D
S
P
G
E
V
P
L
G
E
E
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
63.6
N.A.
80
79.8
N.A.
N.A.
63.1
21.1
56.4
N.A.
N.A.
34.3
31.9
37.4
Protein Similarity:
100
99.8
98
68.8
N.A.
88.5
88.3
N.A.
N.A.
75.3
39.8
71.9
N.A.
N.A.
50.4
45.7
55
P-Site Identity:
100
100
100
53.3
N.A.
46.6
46.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
0
26.6
0
P-Site Similarity:
100
100
100
73.3
N.A.
60
60
N.A.
N.A.
20
26.6
33.3
N.A.
N.A.
33.3
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
34
0
0
42
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
17
9
9
0
9
0
0
17
0
9
50
17
9
0
% D
% Glu:
9
0
0
0
34
9
25
0
0
0
17
42
9
0
0
% E
% Phe:
0
9
0
0
0
34
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
0
9
17
9
0
0
9
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
25
0
0
0
0
50
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
9
0
0
0
59
% I
% Lys:
0
0
50
59
25
9
0
0
9
0
0
0
0
9
0
% K
% Leu:
0
0
0
0
0
17
0
17
0
9
34
0
0
0
17
% L
% Met:
0
9
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
9
0
0
17
9
9
0
0
0
9
9
% N
% Pro:
0
0
0
9
9
0
0
9
9
0
0
0
9
0
9
% P
% Gln:
0
0
17
9
0
0
0
0
9
0
0
9
9
17
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
9
9
9
0
0
50
9
9
9
0
50
0
0
% S
% Thr:
0
9
0
0
0
0
25
0
9
34
9
0
0
0
9
% T
% Val:
0
34
0
0
0
0
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _