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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A23
All Species:
34.24
Human Site:
S409
Identified Species:
57.95
UniProt:
Q9BV35
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BV35
NP_077008.2
468
52378
S409
T
R
M
Q
A
Q
A
S
I
E
G
G
P
Q
L
Chimpanzee
Pan troglodytes
XP_524071
785
87514
S590
T
R
M
Q
A
Q
A
S
I
E
G
G
P
Q
L
Rhesus Macaque
Macaca mulatta
XP_001088378
468
52373
S409
T
R
M
Q
A
Q
A
S
I
E
G
G
P
Q
L
Dog
Lupus familis
XP_542138
468
52473
S409
T
R
M
Q
A
Q
A
S
I
E
G
A
P
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQS1
467
52478
S408
T
R
M
Q
A
Q
A
S
I
E
G
G
P
Q
V
Rat
Rattus norvegicus
Q8K3P6
469
52677
S410
T
R
M
Q
A
Q
A
S
I
E
G
A
P
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519699
472
53241
S413
T
R
M
Q
A
Q
A
S
I
E
G
A
P
Q
L
Chicken
Gallus gallus
XP_422180
475
52468
Q414
A
L
V
R
T
R
M
Q
A
Q
A
S
V
E
G
Frog
Xenopus laevis
Q7ZYD5
514
56789
S455
T
R
M
Q
A
E
A
S
V
E
G
A
P
Q
M
Zebra Danio
Brachydanio rerio
Q66L49
477
53337
S419
T
R
M
Q
A
M
A
S
M
E
G
S
E
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
I475
T
R
L
Q
A
L
S
I
T
R
Y
S
P
Q
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
K378
A
I
Y
C
I
L
K
K
E
G
A
G
G
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
I323
P
E
A
F
A
G
I
I
D
R
D
G
L
I
G
Baker's Yeast
Sacchar. cerevisiae
P48233
545
61252
R481
P
I
N
L
L
R
T
R
L
Q
A
Q
G
T
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.3
99.7
95
N.A.
93.5
63.1
N.A.
87.7
62.1
61
62.8
N.A.
N.A.
N.A.
40.1
N.A.
Protein Similarity:
100
58.2
100
97.2
N.A.
97
75.6
N.A.
93.2
78.5
73.1
79.2
N.A.
N.A.
N.A.
57.9
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
80
N.A.
93.3
0
73.3
66.6
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
33.3
93.3
80
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
27.1
N.A.
22.4
28.9
N.A.
Protein Similarity:
N.A.
45.3
N.A.
39.3
48.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
79
0
65
0
8
0
22
29
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
8
65
0
0
8
15
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
65
43
15
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
8
0
8
15
50
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
0
8
8
8
8
15
0
0
8
0
0
0
8
8
36
% L
% Met:
0
0
65
0
0
8
8
0
8
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
0
0
0
0
0
0
0
0
0
0
0
65
0
8
% P
% Gln:
0
0
0
72
0
50
0
8
0
15
0
8
0
65
0
% Q
% Arg:
0
72
0
8
0
15
0
8
0
15
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
65
0
0
0
22
0
0
0
% S
% Thr:
72
0
0
0
8
0
8
0
8
0
0
0
0
8
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _