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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A23 All Species: 40
Human Site: S124 Identified Species: 67.69
UniProt: Q9BV35 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV35 NP_077008.2 468 52378 S124 Q A E K I L H S M D R D G T M
Chimpanzee Pan troglodytes XP_524071 785 87514 S305 Q A E K I L H S M D R D G T M
Rhesus Macaque Macaca mulatta XP_001088378 468 52373 S124 Q A E K I L H S M D R D G T M
Dog Lupus familis XP_542138 468 52473 S124 Q A E K I L H S M D R D G T M
Cat Felis silvestris
Mouse Mus musculus Q6GQS1 467 52478 S123 Q A E K I L H S M D R D G T M
Rat Rattus norvegicus Q8K3P6 469 52677 S125 Q A E K I L K S M D K N G T M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519699 472 53241 S128 Q A E K I L H S M D R D G T M
Chicken Gallus gallus XP_422180 475 52468 S133 Q A E K I L Q S I D A D G T M
Frog Xenopus laevis Q7ZYD5 514 56789 S170 Q A E K I L K S M D K N G T M
Zebra Danio Brachydanio rerio Q66L49 477 53337 S134 D A E K I L H S I D V D G T M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20799 588 66319 K187 K A Q H I V N K M D Q T G S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 G101 P P G R R G R G S E E E E A E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 D46 L R N P A R G D F G L G R F A
Baker's Yeast Sacchar. cerevisiae P48233 545 61252 S127 N E L N H E L S N E K M N K F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.3 99.7 95 N.A. 93.5 63.1 N.A. 87.7 62.1 61 62.8 N.A. N.A. N.A. 40.1 N.A.
Protein Similarity: 100 58.2 100 97.2 N.A. 97 75.6 N.A. 93.2 78.5 73.1 79.2 N.A. N.A. N.A. 57.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 100 80 80 80 N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 86.6 93.3 86.6 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. 27.1 N.A. 22.4 28.9 N.A.
Protein Similarity: N.A. 45.3 N.A. 39.3 48.2 N.A.
P-Site Identity: N.A. 0 N.A. 0 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 79 0 0 8 0 0 0 0 0 8 0 0 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 0 79 0 58 0 0 0 % D
% Glu: 0 8 72 0 0 8 0 0 0 15 8 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 8 % F
% Gly: 0 0 8 0 0 8 8 8 0 8 0 8 79 0 0 % G
% His: 0 0 0 8 8 0 50 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 79 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 8 0 0 72 0 0 15 8 0 0 22 0 0 8 0 % K
% Leu: 8 0 8 0 0 72 8 0 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 65 0 0 8 0 0 72 % M
% Asn: 8 0 8 8 0 0 8 0 8 0 0 15 8 0 0 % N
% Pro: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 65 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 0 8 8 8 8 0 0 0 43 0 8 0 0 % R
% Ser: 0 0 0 0 0 0 0 79 8 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 72 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _