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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG12 All Species: 31.52
Human Site: Y263 Identified Species: 53.33
UniProt: Q9BV10 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV10 NP_077010.1 488 54655 Y263 G T S P L L W Y F Y S A L P R
Chimpanzee Pan troglodytes XP_001139922 488 54695 Y263 G T S P L L W Y F Y S A L P R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848418 491 54333 Y265 G T S P L L W Y F Y S A L P R
Cat Felis silvestris
Mouse Mus musculus Q8VDB2 483 53807 N251 L G Y N T V L N K S S N W G T
Rat Rattus norvegicus NP_001101574 488 54690 Y264 G T S P L L W Y F Y S A L P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505566 492 55335 Y265 G T S P A L W Y V Y S A L P R
Chicken Gallus gallus XP_001232188 340 38807 A118 F F W Y F Y S A L P R A L G C
Frog Xenopus laevis Q4V7R2 531 61428 Y299 G S H P W H W Y I T Q G V P V
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 Y293 G S H P W H W Y W T Q G L P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VH78 678 76534 Y251 G T S P F L W Y F Y S A L P R
Honey Bee Apis mellifera XP_001122829 360 40954 G138 A E L A M L L G L F L L Y D I
Nematode Worm Caenorhab. elegans Q23361 492 57131 F259 T Q P F L W Y F Y S A L P R C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001077448 497 57174 Y266 G T H S I H W Y F T S A L P R
Baker's Yeast Sacchar. cerevisiae P53730 551 62654 Y279 G V E P V T A Y F T H Y L R M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 N.A. 80 N.A. 77.2 79.5 N.A. 65.2 47.1 21 21.2 N.A. 36.4 36.2 37.4 N.A.
Protein Similarity: 100 98.7 N.A. 87.5 N.A. 85.4 87.5 N.A. 78.8 56.5 38.6 38 N.A. 49.4 51.2 56.2 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 6.6 100 N.A. 86.6 13.3 33.3 40 N.A. 93.3 6.6 6.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 13.3 100 N.A. 86.6 13.3 46.6 53.3 N.A. 93.3 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 8 8 0 0 8 58 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 8 0 8 15 0 0 8 50 8 0 0 0 0 0 % F
% Gly: 72 8 0 0 0 0 0 8 0 0 0 15 0 15 0 % G
% His: 0 0 22 0 0 22 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 36 50 15 0 15 0 8 15 72 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % N
% Pro: 0 0 8 65 0 0 0 0 0 8 0 0 8 65 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 15 50 % R
% Ser: 0 15 43 8 0 0 8 0 0 15 58 0 0 0 0 % S
% Thr: 8 50 0 0 8 8 0 0 0 29 0 0 0 0 8 % T
% Val: 0 8 0 0 8 8 0 0 8 0 0 0 8 0 15 % V
% Trp: 0 0 8 0 15 8 65 0 8 0 0 0 8 0 0 % W
% Tyr: 0 0 8 8 0 8 8 72 8 43 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _