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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG12 All Species: 10.91
Human Site: S338 Identified Species: 18.46
UniProt: Q9BV10 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BV10 NP_077010.1 488 54655 S338 L L N N Y K K S W L Y K A G S
Chimpanzee Pan troglodytes XP_001139922 488 54695 S338 L L N N Y K K S W L Y K A G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848418 491 54333 S340 L L N N Y R K S W L Y K A G S
Cat Felis silvestris
Mouse Mus musculus Q8VDB2 483 53807 A326 P V L N I M A A R G C T Y I L
Rat Rattus norvegicus NP_001101574 488 54690 P339 V L N K K S W P Y K V R A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505566 492 55335 K340 A P L N N Y R K S W L Y K V G
Chicken Gallus gallus XP_001232188 340 38807 K193 Y R K S W L Y K L G S L F V V
Frog Xenopus laevis Q4V7R2 531 61428 K374 S N L K R W K K A A V G F L V
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 K368 A K L Q A W R K A A A G A L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VH78 678 76534 K326 R I W M N S A K S T W H S F L
Honey Bee Apis mellifera XP_001122829 360 40954 A213 F L W Y F Y S A L P R G L A F
Nematode Worm Caenorhab. elegans Q23361 492 57131 S334 M L I N R H K S F F R M I L F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001077448 497 57174 K341 R I Y N N R K K T I W K L V N
Baker's Yeast Sacchar. cerevisiae P53730 551 62654 N354 G A A H L W E N M K V K K I T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 N.A. 80 N.A. 77.2 79.5 N.A. 65.2 47.1 21 21.2 N.A. 36.4 36.2 37.4 N.A.
Protein Similarity: 100 98.7 N.A. 87.5 N.A. 85.4 87.5 N.A. 78.8 56.5 38.6 38 N.A. 49.4 51.2 56.2 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 6.6 20 N.A. 6.6 0 6.6 6.6 N.A. 0 6.6 26.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 20 40 N.A. 13.3 13.3 6.6 13.3 N.A. 20 20 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 38 31.4 N.A.
Protein Similarity: N.A. N.A. N.A. 58.3 49.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 0 8 0 15 15 15 15 8 0 36 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 8 8 0 0 15 8 15 % F
% Gly: 8 0 0 0 0 0 0 0 0 15 0 22 0 22 8 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 15 8 0 8 0 0 0 0 8 0 0 8 15 0 % I
% Lys: 0 8 8 15 8 15 43 43 0 15 0 36 15 0 0 % K
% Leu: 22 43 29 0 8 8 0 0 15 22 8 8 15 29 29 % L
% Met: 8 0 0 8 0 8 0 0 8 0 0 8 0 0 0 % M
% Asn: 0 8 29 50 22 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 8 8 0 0 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 8 0 0 15 15 15 0 8 0 15 8 0 0 0 % R
% Ser: 8 0 0 8 0 15 8 29 15 0 8 0 8 0 22 % S
% Thr: 0 0 0 0 0 0 0 0 8 8 0 8 0 0 8 % T
% Val: 8 8 0 0 0 0 0 0 0 0 22 0 0 22 15 % V
% Trp: 0 0 15 0 8 22 8 0 22 8 15 0 0 0 0 % W
% Tyr: 8 0 8 8 22 15 8 0 8 0 22 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _