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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD1
All Species:
21.21
Human Site:
S200
Identified Species:
31.11
UniProt:
Q9BUP0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUP0
NP_079478.1
239
26928
S200
E
A
K
V
Q
A
L
S
S
A
S
K
F
E
A
Chimpanzee
Pan troglodytes
XP_001143163
390
43806
S351
E
A
K
V
Q
A
L
S
S
A
S
K
F
E
A
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
E130
M
Y
E
E
K
A
R
E
K
E
K
P
T
G
P
Dog
Lupus familis
XP_543290
141
15950
K124
E
R
K
Q
E
E
E
K
R
R
I
R
Q
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4J1
240
26981
S201
E
A
K
A
Q
A
L
S
C
S
S
K
F
E
A
Rat
Rattus norvegicus
Q4FZY0
239
26741
N201
E
A
K
V
Q
A
I
N
V
S
S
R
F
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
E153
E
E
K
K
K
Q
A
E
E
M
K
Q
R
K
A
Chicken
Gallus gallus
NP_001026943
238
26908
S199
E
A
K
V
Q
A
L
S
S
A
S
K
F
E
A
Frog
Xenopus laevis
NP_001085773
231
26398
S192
E
A
K
V
Q
A
L
S
S
S
S
K
F
E
A
Zebra Danio
Brachydanio rerio
XP_683253
227
26230
S188
E
A
K
A
Q
A
L
S
V
R
S
K
F
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
L179
E
A
K
I
E
Q
Q
L
R
T
N
K
F
H
D
Honey Bee
Apis mellifera
XP_624640
195
22857
E177
E
E
R
K
R
E
E
E
E
K
A
E
R
R
A
Nematode Worm
Caenorhab. elegans
O16305
149
16806
D132
M
I
R
E
A
D
I
D
G
D
G
Q
V
N
Y
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
Q166
H
Q
E
I
L
D
E
Q
E
E
R
R
Q
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
F149
D
G
D
G
R
I
N
F
Q
E
F
A
K
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P61859
149
16978
D132
M
I
R
E
A
D
Q
D
G
D
G
R
I
D
Y
Conservation
Percent
Protein Identity:
100
61.2
23.8
53.1
N.A.
81.2
65.6
N.A.
51.4
74.4
69.4
63.5
N.A.
48.5
47.7
21.3
50.2
Protein Similarity:
100
61.2
38.4
57.7
N.A.
87.9
78.6
N.A.
61
84
83.2
80.7
N.A.
59.4
61.9
38.4
61.5
P-Site Identity:
100
100
6.6
20
N.A.
80
60
N.A.
20
100
93.3
80
N.A.
33.3
13.3
0
13.3
P-Site Similarity:
100
100
20
33.3
N.A.
86.6
86.6
N.A.
40
100
100
80
N.A.
53.3
40
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
20.9
Protein Similarity:
N.A.
N.A.
N.A.
37.2
N.A.
38.9
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
13
13
50
7
0
0
19
7
7
0
13
63
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
0
19
0
13
0
13
0
0
0
7
7
% D
% Glu:
69
13
13
19
13
13
19
19
19
19
0
7
0
50
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
0
50
0
0
% F
% Gly:
0
7
0
7
0
0
0
0
13
0
13
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
13
0
13
0
7
13
0
0
0
7
0
7
0
7
% I
% Lys:
0
0
63
13
13
0
0
7
7
7
13
44
7
7
0
% K
% Leu:
0
0
0
0
7
0
38
7
0
0
0
0
0
0
0
% L
% Met:
19
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% P
% Gln:
0
7
0
7
44
13
13
7
7
0
0
13
13
0
0
% Q
% Arg:
0
7
19
0
13
0
7
0
13
13
7
25
13
7
0
% R
% Ser:
0
0
0
0
0
0
0
38
25
19
44
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% T
% Val:
0
0
0
32
0
0
0
0
13
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _