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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3C
All Species:
22.42
Human Site:
T269
Identified Species:
44.85
UniProt:
Q9BUI4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUI4
NP_006459.3
534
60612
T269
T
S
S
E
I
V
R
T
M
L
R
M
S
E
I
Chimpanzee
Pan troglodytes
XP_001161518
508
57536
E265
R
M
D
Q
T
S
S
E
I
V
R
T
M
L
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540277
534
60596
T269
T
S
S
E
I
V
R
T
M
L
R
M
S
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D483
533
60687
T268
T
S
S
E
I
V
R
T
M
L
R
M
S
E
I
Rat
Rattus norvegicus
Q5XIL3
533
60524
T268
T
S
S
E
I
V
R
T
M
L
R
M
S
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519209
341
37130
P98
S
R
S
F
P
N
G
P
V
G
R
G
S
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086474
529
60253
T264
T
S
S
E
I
V
R
T
M
L
R
M
S
E
V
Zebra Danio
Brachydanio rerio
Q7ZUX1
539
60470
T274
T
S
G
E
I
V
R
T
M
L
R
M
S
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650207
522
59801
V268
L
S
N
Q
I
T
F
V
E
I
K
Q
A
I
E
Honey Bee
Apis mellifera
XP_394638
432
50172
L189
Y
P
L
L
T
Q
H
L
D
Q
Y
L
R
L
I
Nematode Worm
Caenorhab. elegans
NP_491807
544
61746
M275
T
Q
N
V
A
H
L
M
F
K
I
N
E
T
R
Sea Urchin
Strong. purpuratus
XP_001190037
532
61023
V266
D
K
S
A
G
D
V
V
A
T
M
L
R
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.2
N.A.
93.8
93.8
N.A.
42.8
N.A.
77.7
65.6
N.A.
33.9
34.4
23.1
49.2
Protein Similarity:
100
95.1
N.A.
97.7
N.A.
96.6
96.6
N.A.
49.6
N.A.
88.5
79.9
N.A.
54.3
53.9
47.6
71.3
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
20
N.A.
93.3
86.6
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
33.3
N.A.
100
93.3
N.A.
46.6
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
0
0
9
9
0
0
0
9
50
9
% E
% Phe:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
9
0
0
9
0
9
0
9
0
% G
% His:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
59
0
0
0
9
9
9
0
0
9
42
% I
% Lys:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% K
% Leu:
9
0
9
9
0
0
9
9
0
50
0
17
0
17
0
% L
% Met:
0
9
0
0
0
0
0
9
50
0
9
50
9
9
0
% M
% Asn:
0
0
17
0
0
9
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
17
0
9
0
0
0
9
0
9
0
0
0
% Q
% Arg:
9
9
0
0
0
0
50
0
0
0
67
0
17
0
25
% R
% Ser:
9
59
59
0
0
9
9
0
0
0
0
0
59
0
9
% S
% Thr:
59
0
0
0
17
9
0
50
0
9
0
9
0
9
0
% T
% Val:
0
0
0
9
0
50
9
17
9
9
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _