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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTPAL All Species: 21.82
Human Site: S18 Identified Species: 40
UniProt: Q9BTX7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTX7 NP_001034288.1 342 38515 S18 S P S V A S L S E N E L P P P
Chimpanzee Pan troglodytes XP_514665 342 38428 S18 S P S V A S L S E N E L P P P
Rhesus Macaque Macaca mulatta XP_001110493 342 38437 S18 S P S V A S L S E N E L P P P
Dog Lupus familis XP_534426 342 38407 S18 S P S A A S L S E N E L P P P
Cat Felis silvestris
Mouse Mus musculus Q9D3D0 343 38817 S18 S P S V A S L S E N E L P L P
Rat Rattus norvegicus A6JUQ6 327 37898 N23 A R L E L N E N P D T L H Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510973 445 49726 A18 K A P R P A R A S G Y V C S L
Chicken Gallus gallus NP_001026025 300 33914 S18 S P S A G S P S D P E A L P D
Frog Xenopus laevis Q5M7E1 332 38511 N23 G R L E L N E N P D T L H Q D
Zebra Danio Brachydanio rerio Q5SPP0 329 38101 N23 A K V E L K E N P D T L H Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03606 719 81064 S194 E T T S A T D S A I E M K E L
Sea Urchin Strong. purpuratus XP_780795 286 33208 L18 G L K K K A E L E L G E T P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P33324 310 36055 P19 I C S P N A L P G T P G N L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.5 94.7 N.A. 94.1 33.3 N.A. 61.5 73.3 33.6 33.3 N.A. N.A. N.A. 20.4 31.5
Protein Similarity: 100 99.7 99.1 96.1 N.A. 98.2 49.4 N.A. 66.2 79.2 49.1 49.7 N.A. N.A. N.A. 30 50.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 0 46.6 6.6 6.6 N.A. N.A. N.A. 20 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 33.3 N.A. 20 53.3 26.6 26.6 N.A. N.A. N.A. 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 16 47 24 0 8 8 0 0 8 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 8 24 0 0 0 0 31 % D
% Glu: 8 0 0 24 0 0 31 0 47 0 54 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 0 8 0 0 0 8 8 8 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 8 8 8 8 8 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 16 0 24 0 47 8 0 8 0 62 8 16 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 8 16 0 24 0 39 0 0 8 0 0 % N
% Pro: 0 47 8 8 8 0 8 8 24 8 8 0 39 47 39 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 % Q
% Arg: 0 16 0 8 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 47 0 54 8 0 47 0 54 8 0 0 0 0 8 8 % S
% Thr: 0 8 8 0 0 8 0 0 0 8 24 0 8 0 8 % T
% Val: 0 0 8 31 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _