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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES2
All Species:
1.52
Human Site:
T300
Identified Species:
3.03
UniProt:
Q9BTV7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV7
NP_112492.2
478
52235
T300
L
G
S
D
V
G
D
T
L
E
Y
N
P
N
L
Chimpanzee
Pan troglodytes
XP_512059
702
76038
Y526
D
L
G
D
F
M
D
Y
D
P
N
L
L
D
D
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
R242
W
P
C
G
K
H
K
R
V
L
I
F
A
S
Y
Dog
Lupus familis
XP_855204
432
47740
P265
N
P
N
L
L
D
D
P
Q
W
P
C
G
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3M5
481
52692
A303
L
G
S
D
G
G
D
A
V
E
Y
N
P
N
L
Rat
Rattus norvegicus
XP_001059501
427
47203
H267
P
Q
W
P
C
G
K
H
K
R
V
L
I
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506144
362
41389
V205
P
C
G
K
H
K
R
V
L
I
F
A
S
Y
M
Chicken
Gallus gallus
XP_417406
469
52163
V291
I
G
S
E
A
G
E
V
A
E
Y
D
P
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919825
505
55506
S328
D
T
G
V
D
E
L
S
E
Y
D
P
N
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
A514
E
N
N
N
R
N
S
A
T
S
P
T
P
D
M
Honey Bee
Apis mellifera
XP_623648
562
63688
K376
L
S
F
N
T
D
S
K
V
Y
D
W
D
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
K256
L
S
L
G
K
H
R
K
L
L
T
F
S
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
79.5
75.3
N.A.
87.7
78.2
N.A.
64.8
76.9
N.A.
51.4
N.A.
26
33.8
N.A.
30.5
Protein Similarity:
100
50.4
80.5
78.8
N.A.
90.6
81.1
N.A.
69.6
82.8
N.A.
63.3
N.A.
41.2
49.2
N.A.
49.1
P-Site Identity:
100
13.3
0
6.6
N.A.
80
6.6
N.A.
6.6
53.3
N.A.
6.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
20
13.3
20
N.A.
86.6
6.6
N.A.
20
80
N.A.
13.3
N.A.
33.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
17
9
0
0
9
9
0
9
% A
% Cys:
0
9
9
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
17
0
0
25
9
17
34
0
9
0
17
9
9
17
9
% D
% Glu:
9
0
0
9
0
9
9
0
9
25
0
0
0
9
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
9
17
0
9
0
% F
% Gly:
0
25
25
17
9
34
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
9
17
0
9
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% I
% Lys:
0
0
0
9
17
9
17
17
9
0
0
0
0
9
0
% K
% Leu:
34
9
9
9
9
0
9
0
25
17
0
17
9
9
34
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
17
% M
% Asn:
9
9
17
17
0
9
0
0
0
0
9
17
9
25
0
% N
% Pro:
17
17
0
9
0
0
0
9
0
9
17
9
34
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
9
0
17
9
0
9
0
0
0
0
0
% R
% Ser:
0
17
25
0
0
0
17
9
0
9
0
0
17
17
0
% S
% Thr:
0
9
0
0
9
0
0
9
9
0
9
9
0
0
0
% T
% Val:
0
0
0
9
9
0
0
17
25
0
9
0
0
0
0
% V
% Trp:
9
0
9
0
0
0
0
0
0
9
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
17
25
0
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _