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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CABLES2 All Species: 5.45
Human Site: S269 Identified Species: 10.91
UniProt: Q9BTV7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTV7 NP_112492.2 478 52235 S269 L L P T P R P S V P R T L P G
Chimpanzee Pan troglodytes XP_512059 702 76038 R495 T S S F S Q F R N L S H R S L
Rhesus Macaque Macaca mulatta XP_001115094 400 44686 A211 A P T K S A P A S T E L G G D
Dog Lupus familis XP_855204 432 47740 T234 A P A K S A P T G A E L G S L
Cat Felis silvestris
Mouse Mus musculus Q8K3M5 481 52692 S272 L L P Q P R P S I P R A P P G
Rat Rattus norvegicus XP_001059501 427 47203 T236 K P V P T K S T P A G T E L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506144 362 41389 G174 T A K T V P T G T E L G S E M
Chicken Gallus gallus XP_417406 469 52163 G260 A V P S C R A G A S R S L P G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919825 505 55506 P297 D I S T A Q M P M S R N R I N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610890 717 79307 F483 A S A N P S I F E N Q M E I T
Honey Bee Apis mellifera XP_623648 562 63688 I345 L I S N K H P I V S R C L S Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790638 413 47121 E225 Q W D K I E V E G H P V D H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.8 79.5 75.3 N.A. 87.7 78.2 N.A. 64.8 76.9 N.A. 51.4 N.A. 26 33.8 N.A. 30.5
Protein Similarity: 100 50.4 80.5 78.8 N.A. 90.6 81.1 N.A. 69.6 82.8 N.A. 63.3 N.A. 41.2 49.2 N.A. 49.1
P-Site Identity: 100 0 6.6 6.6 N.A. 73.3 13.3 N.A. 6.6 40 N.A. 13.3 N.A. 6.6 33.3 N.A. 0
P-Site Similarity: 100 6.6 13.3 13.3 N.A. 80 26.6 N.A. 6.6 60 N.A. 33.3 N.A. 13.3 40 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 17 0 9 17 9 9 9 17 0 9 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 0 9 0 0 0 0 0 0 0 0 0 9 0 9 % D
% Glu: 0 0 0 0 0 9 0 9 9 9 17 0 17 9 0 % E
% Phe: 0 0 0 9 0 0 9 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 17 17 0 9 9 17 9 34 % G
% His: 0 0 0 0 0 9 0 0 0 9 0 9 0 9 0 % H
% Ile: 0 17 0 0 9 0 9 9 9 0 0 0 0 17 0 % I
% Lys: 9 0 9 25 9 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 25 17 0 0 0 0 0 0 0 9 9 17 25 9 17 % L
% Met: 0 0 0 0 0 0 9 0 9 0 0 9 0 0 9 % M
% Asn: 0 0 0 17 0 0 0 0 9 9 0 9 0 0 9 % N
% Pro: 0 25 25 9 25 9 42 9 9 17 9 0 9 25 9 % P
% Gln: 9 0 0 9 0 17 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 25 0 9 0 0 42 0 17 0 0 % R
% Ser: 0 17 25 9 25 9 9 17 9 25 9 9 9 25 0 % S
% Thr: 17 0 9 25 9 0 9 17 9 9 0 17 0 0 9 % T
% Val: 0 9 9 0 9 0 9 0 17 0 0 9 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _