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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES2
All Species:
2.73
Human Site:
S257
Identified Species:
5.45
UniProt:
Q9BTV7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV7
NP_112492.2
478
52235
S257
N
A
L
V
T
H
K
S
D
S
H
G
L
L
P
Chimpanzee
Pan troglodytes
XP_512059
702
76038
N483
N
A
F
G
A
R
R
N
T
I
D
S
T
S
S
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
S199
V
P
R
T
L
P
G
S
R
H
K
P
A
P
T
Dog
Lupus familis
XP_855204
432
47740
S222
V
P
R
T
L
P
A
S
R
Y
K
A
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3M5
481
52692
N260
N
A
L
V
I
H
K
N
D
S
H
G
L
L
P
Rat
Rattus norvegicus
XP_001059501
427
47203
P224
P
S
I
P
R
A
P
P
G
S
R
H
K
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506144
362
41389
R162
P
R
T
L
P
G
S
R
Y
K
S
L
T
A
K
Chicken
Gallus gallus
XP_417406
469
52163
A248
N
A
L
V
V
R
K
A
D
S
H
S
A
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919825
505
55506
S285
N
A
L
V
R
L
K
S
S
G
Q
T
D
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
K471
R
Q
Y
E
K
E
R
K
K
H
G
N
A
S
A
Honey Bee
Apis mellifera
XP_623648
562
63688
N333
K
K
L
H
F
S
D
N
E
T
I
E
L
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
N213
I
R
K
M
T
L
T
N
V
S
P
L
Q
W
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
79.5
75.3
N.A.
87.7
78.2
N.A.
64.8
76.9
N.A.
51.4
N.A.
26
33.8
N.A.
30.5
Protein Similarity:
100
50.4
80.5
78.8
N.A.
90.6
81.1
N.A.
69.6
82.8
N.A.
63.3
N.A.
41.2
49.2
N.A.
49.1
P-Site Identity:
100
13.3
6.6
6.6
N.A.
86.6
6.6
N.A.
0
60
N.A.
40
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
26.6
6.6
6.6
N.A.
93.3
20
N.A.
6.6
73.3
N.A.
46.6
N.A.
6.6
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
9
9
9
9
0
0
0
9
34
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
25
0
9
0
9
0
9
% D
% Glu:
0
0
0
9
0
9
0
0
9
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
9
0
9
9
9
17
0
0
0
% G
% His:
0
0
0
9
0
17
0
0
0
17
25
9
0
0
0
% H
% Ile:
9
0
9
0
9
0
0
0
0
9
9
0
0
17
0
% I
% Lys:
9
9
9
0
9
0
34
9
9
9
17
0
9
0
9
% K
% Leu:
0
0
42
9
17
17
0
0
0
0
0
17
25
17
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
0
0
0
0
0
0
34
0
0
0
9
0
0
0
% N
% Pro:
17
17
0
9
9
17
9
9
0
0
9
9
0
25
25
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
9
17
17
0
17
17
17
9
17
0
9
0
0
0
0
% R
% Ser:
0
9
0
0
0
9
9
34
9
42
9
17
0
17
25
% S
% Thr:
0
0
9
17
17
0
9
0
9
9
0
9
17
0
9
% T
% Val:
17
0
0
34
9
0
0
0
9
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _