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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM43
All Species:
27.27
Human Site:
Y122
Identified Species:
54.55
UniProt:
Q9BTV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV4
NP_077310.1
400
44876
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Chimpanzee
Pan troglodytes
XP_516299
400
44829
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Rhesus Macaque
Macaca mulatta
XP_001090994
400
44870
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Dog
Lupus familis
XP_541751
400
44872
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS1
400
44765
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Rat
Rattus norvegicus
Q5XIP9
400
44756
Y122
L
R
R
H
V
E
M
Y
Q
W
V
E
T
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507428
248
28322
Chicken
Gallus gallus
XP_414378
400
44849
Y122
L
K
R
K
V
E
M
Y
Q
W
V
E
Y
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998403
282
31264
Y27
K
T
E
T
T
Y
S
Y
N
T
E
W
R
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSB9
376
42755
G118
H
N
Y
G
D
S
V
G
T
T
H
S
D
S
R
Honey Bee
Apis mellifera
XP_624625
406
46544
Q132
V
K
L
K
R
R
V
Q
M
Y
Q
W
V
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798642
410
46142
L128
I
S
V
R
A
V
K
L
R
R
H
V
Q
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
92.5
N.A.
93
91.5
N.A.
48.2
70
N.A.
37.7
N.A.
32.7
34.2
N.A.
31.7
Protein Similarity:
100
99.5
97.7
96.7
N.A.
97
95.7
N.A.
53.7
85.5
N.A.
52.5
N.A.
50.5
55.1
N.A.
52.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
73.3
N.A.
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
N.A.
13.3
N.A.
6.6
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
9
% D
% Glu:
0
0
9
0
0
59
0
0
0
0
9
59
0
67
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
9
0
0
50
0
0
0
0
0
0
17
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
9
17
0
17
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
59
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
59
0
9
0
0
0
0
9
0
% M
% Asn:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
59
0
9
0
9
0
0
% Q
% Arg:
0
50
59
9
9
9
0
0
9
9
0
0
9
0
9
% R
% Ser:
0
9
0
0
0
9
9
0
0
0
0
9
0
17
0
% S
% Thr:
0
9
0
9
9
0
0
0
9
17
0
0
50
0
0
% T
% Val:
9
0
9
0
59
9
17
0
0
0
59
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
59
0
17
0
0
0
% W
% Tyr:
0
0
9
0
0
9
0
67
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _