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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM43
All Species:
30
Human Site:
T149
Identified Species:
60
UniProt:
Q9BTV4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV4
NP_077310.1
400
44876
T149
E
T
R
Y
S
Y
N
T
E
W
R
S
E
I
I
Chimpanzee
Pan troglodytes
XP_516299
400
44829
T149
E
T
R
Y
S
Y
N
T
E
W
R
S
E
I
I
Rhesus Macaque
Macaca mulatta
XP_001090994
400
44870
T149
E
T
R
Y
S
Y
N
T
E
W
R
S
E
I
I
Dog
Lupus familis
XP_541751
400
44872
T149
E
T
R
Y
S
Y
N
T
E
W
R
S
E
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS1
400
44765
T149
E
T
K
Y
S
Y
N
T
E
W
R
S
E
I
V
Rat
Rattus norvegicus
Q5XIP9
400
44756
T149
E
T
K
Y
S
Y
N
T
E
W
R
S
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507428
248
28322
F20
H
L
S
V
V
P
L
F
K
F
S
D
T
S
N
Chicken
Gallus gallus
XP_414378
400
44849
T149
E
T
K
Y
S
Y
N
T
E
W
K
P
E
V
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998403
282
31264
A54
H
M
N
P
S
E
M
A
V
E
S
V
T
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSB9
376
42755
N145
V
D
S
R
N
F
Y
N
R
H
G
H
T
N
P
Honey Bee
Apis mellifera
XP_624625
406
46544
T159
E
K
H
Y
Y
Y
T
T
E
W
K
D
K
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798642
410
46142
K155
D
I
Q
Y
T
Y
T
K
E
W
R
S
E
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
92.5
N.A.
93
91.5
N.A.
48.2
70
N.A.
37.7
N.A.
32.7
34.2
N.A.
31.7
Protein Similarity:
100
99.5
97.7
96.7
N.A.
97
95.7
N.A.
53.7
85.5
N.A.
52.5
N.A.
50.5
55.1
N.A.
52.4
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
0
66.6
N.A.
6.6
N.A.
0
40
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
20
N.A.
13.3
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
0
0
0
0
17
0
0
0
% D
% Glu:
67
0
0
0
0
9
0
0
75
9
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
17
0
9
0
0
0
0
0
0
9
0
9
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
0
59
34
% I
% Lys:
0
9
25
0
0
0
0
9
9
0
17
0
9
0
0
% K
% Leu:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% L
% Met:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
59
9
0
0
0
0
0
9
9
% N
% Pro:
0
0
0
9
0
9
0
0
0
0
0
9
0
0
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
34
9
0
0
0
0
9
0
59
0
0
0
0
% R
% Ser:
0
0
17
0
67
0
0
0
0
0
17
59
0
9
0
% S
% Thr:
0
59
0
0
9
0
17
67
0
0
0
0
25
0
0
% T
% Val:
9
0
0
9
9
0
0
0
9
0
0
9
0
17
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% W
% Tyr:
0
0
0
75
9
75
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _