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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM43
All Species:
27.88
Human Site:
S305
Identified Species:
55.76
UniProt:
Q9BTV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV4
NP_077310.1
400
44876
S305
H
R
E
L
R
S
N
S
M
K
T
W
G
L
R
Chimpanzee
Pan troglodytes
XP_516299
400
44829
S305
H
R
E
L
R
S
N
S
M
K
T
W
G
L
R
Rhesus Macaque
Macaca mulatta
XP_001090994
400
44870
S305
H
R
E
L
R
S
N
S
M
K
T
W
G
L
R
Dog
Lupus familis
XP_541751
400
44872
S305
H
R
E
R
K
S
N
S
L
K
T
W
G
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS1
400
44765
S305
R
R
E
Q
K
S
N
S
M
K
T
W
G
L
R
Rat
Rattus norvegicus
Q5XIP9
400
44756
S305
R
R
E
Q
K
S
N
S
M
K
T
W
G
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507428
248
28322
N174
E
W
K
A
E
V
V
N
S
R
N
F
D
R
E
Chicken
Gallus gallus
XP_414378
400
44849
T305
Q
K
E
H
E
S
N
T
M
K
T
W
A
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998403
282
31264
T208
F
L
S
I
S
L
S
T
R
V
I
H
T
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSB9
376
42755
N299
I
F
F
G
V
T
C
N
T
K
I
L
R
L
L
Honey Bee
Apis mellifera
XP_624625
406
46544
G314
W
R
T
W
S
I
R
G
L
G
W
L
V
L
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798642
410
46142
T311
L
R
H
L
N
L
Q
T
S
L
T
W
S
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
92.5
N.A.
93
91.5
N.A.
48.2
70
N.A.
37.7
N.A.
32.7
34.2
N.A.
31.7
Protein Similarity:
100
99.5
97.7
96.7
N.A.
97
95.7
N.A.
53.7
85.5
N.A.
52.5
N.A.
50.5
55.1
N.A.
52.4
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
0
60
N.A.
6.6
N.A.
13.3
13.3
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
26.6
73.3
N.A.
26.6
N.A.
26.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
0
59
0
17
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
9
9
9
0
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
0
0
0
9
0
0
0
9
0
9
0
0
50
0
0
% G
% His:
34
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
0
9
0
9
0
0
0
0
17
0
0
0
0
% I
% Lys:
0
9
9
0
25
0
0
0
0
67
0
0
0
0
0
% K
% Leu:
9
9
0
34
0
17
0
0
17
9
0
17
0
92
9
% L
% Met:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
59
17
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
17
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
17
67
0
9
25
0
9
0
9
9
0
0
9
9
67
% R
% Ser:
0
0
9
0
17
59
9
50
17
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
9
0
25
9
0
67
0
9
0
0
% T
% Val:
0
0
0
0
9
9
9
0
0
9
0
0
9
0
9
% V
% Trp:
9
9
0
9
0
0
0
0
0
0
9
67
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _