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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5K
All Species:
12.42
Human Site:
T406
Identified Species:
30.37
UniProt:
Q9BT40
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT40
NP_001129114.1
448
51090
T406
D
I
S
N
I
P
T
T
E
D
E
F
L
L
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117306
555
61812
T513
D
I
S
N
I
P
A
T
E
D
E
F
L
L
C
Dog
Lupus familis
XP_537766
624
69422
T581
N
T
R
D
I
P
E
T
E
D
Q
F
L
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5L6
468
54140
T425
N
I
S
A
I
P
D
T
E
D
Q
F
L
L
C
Rat
Rattus norvegicus
Q9JMC1
1001
107190
G811
E
S
L
P
K
G
H
G
D
F
I
L
G
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
G558
E
S
L
P
K
G
R
G
E
F
I
L
G
Y
Y
Chicken
Gallus gallus
XP_001234813
858
98308
M802
S
A
A
E
I
P
D
M
G
G
K
F
L
L
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573135
508
58954
H427
P
F
E
T
P
S
H
H
R
R
G
R
H
H
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34370
398
45188
A362
I
E
G
S
K
F
L
A
C
E
F
N
N
I
P
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
S401
K
Y
V
L
C
Y
V
S
R
T
M
S
C
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
77.8
57.5
N.A.
72.6
23.7
N.A.
29.5
31.1
N.A.
N.A.
N.A.
30.1
N.A.
21.8
35
Protein Similarity:
100
N.A.
78.7
62.6
N.A.
82.4
31.3
N.A.
39.4
40.3
N.A.
N.A.
N.A.
49.2
N.A.
40.8
54.4
P-Site Identity:
100
N.A.
93.3
60
N.A.
73.3
0
N.A.
6.6
40
N.A.
N.A.
N.A.
0
N.A.
0
0
P-Site Similarity:
100
N.A.
93.3
80
N.A.
86.6
13.3
N.A.
13.3
53.3
N.A.
N.A.
N.A.
0
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
50
% C
% Asp:
20
0
0
10
0
0
20
0
10
40
0
0
0
0
0
% D
% Glu:
20
10
10
10
0
0
10
0
50
10
20
0
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
20
10
50
0
0
0
% F
% Gly:
0
0
10
0
0
20
0
20
10
10
10
0
20
0
0
% G
% His:
0
0
0
0
0
0
20
10
0
0
0
0
10
10
10
% H
% Ile:
10
30
0
0
50
0
0
0
0
0
20
0
0
10
0
% I
% Lys:
10
0
0
0
30
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
20
10
0
0
10
0
0
0
0
20
50
50
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
20
0
0
20
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
10
0
0
20
10
50
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
10
0
20
10
0
10
0
0
0
% R
% Ser:
10
20
30
10
0
10
0
10
0
0
0
10
0
0
0
% S
% Thr:
0
10
0
10
0
0
10
40
0
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
0
20
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _