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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5K
All Species:
22.12
Human Site:
T246
Identified Species:
54.07
UniProt:
Q9BT40
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT40
NP_001129114.1
448
51090
T246
G
R
L
L
F
P
P
T
Y
K
F
D
R
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001117306
555
61812
T353
G
R
L
L
F
P
P
T
Y
K
F
D
R
N
S
Dog
Lupus familis
XP_537766
624
69422
T421
G
P
L
L
F
P
P
T
Y
K
F
D
K
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5L6
468
54140
T264
G
P
L
L
F
P
P
T
Y
K
F
D
R
H
S
Rat
Rattus norvegicus
Q9JMC1
1001
107190
T652
G
P
L
N
F
A
P
T
F
K
F
D
V
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507443
768
84124
T399
G
P
L
T
F
A
P
T
F
K
F
D
V
G
T
Chicken
Gallus gallus
XP_001234813
858
98308
V641
K
F
D
L
H
S
D
V
Y
D
T
R
E
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573135
508
58954
L253
A
L
I
Q
R
D
Q
L
Y
Q
V
R
E
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34370
398
45188
L204
L
L
D
T
R
E
Q
L
K
R
A
L
V
E
R
Sea Urchin
Strong. purpuratus
XP_780987
442
50512
T237
G
L
I
T
F
M
P
T
Y
K
F
D
L
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
77.8
57.5
N.A.
72.6
23.7
N.A.
29.5
31.1
N.A.
N.A.
N.A.
30.1
N.A.
21.8
35
Protein Similarity:
100
N.A.
78.7
62.6
N.A.
82.4
31.3
N.A.
39.4
40.3
N.A.
N.A.
N.A.
49.2
N.A.
40.8
54.4
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
53.3
N.A.
53.3
13.3
N.A.
N.A.
N.A.
13.3
N.A.
0
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
66.6
N.A.
66.6
13.3
N.A.
N.A.
N.A.
26.6
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
20
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
10
10
0
0
10
0
70
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
20
10
0
% E
% Phe:
0
10
0
0
70
0
0
0
20
0
70
0
0
0
0
% F
% Gly:
70
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
10
70
0
0
10
20
10
% K
% Leu:
10
30
60
50
0
0
0
20
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
30
0
% N
% Pro:
0
40
0
0
0
40
70
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
20
0
0
10
0
0
0
10
0
% Q
% Arg:
0
20
0
0
20
0
0
0
0
10
0
20
30
0
10
% R
% Ser:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
60
% S
% Thr:
0
0
0
30
0
0
0
70
0
0
10
0
0
0
20
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
0
30
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _