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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN
All Species:
19.09
Human Site:
T487
Identified Species:
35
UniProt:
Q9BST9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BST9
NP_001015055.1
563
62667
T487
P
P
W
L
A
M
F
T
D
Q
P
A
L
P
N
Chimpanzee
Pan troglodytes
XP_001157465
563
62576
T487
P
P
W
L
A
M
F
T
N
Q
P
A
L
P
N
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
T487
P
P
W
L
A
M
F
T
D
Q
P
A
L
P
N
Dog
Lupus familis
XP_532998
564
62928
T487
P
P
W
L
A
M
F
T
E
Q
P
A
L
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C6B2
564
63022
T487
P
P
W
L
A
M
F
T
D
Q
P
A
L
P
S
Rat
Rattus norvegicus
Q6V7V2
548
61135
F473
P
P
P
W
L
A
M
F
T
D
Q
P
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
S530
A
G
V
A
Y
R
T
S
S
L
D
S
K
L
S
Chicken
Gallus gallus
XP_421541
873
96370
E728
F
L
L
C
Q
Q
K
E
P
A
S
S
L
W
A
Frog
Xenopus laevis
Q5XGX5
612
69089
E463
F
L
I
G
P
Q
E
E
S
A
P
A
P
W
A
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
E484
F
L
I
G
Q
E
E
E
T
E
P
P
H
W
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393113
433
50447
E358
V
I
E
L
Y
S
N
E
D
A
Q
K
W
L
E
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
K440
Q
S
P
K
P
S
R
K
S
I
I
H
E
P
S
Sea Urchin
Strong. purpuratus
XP_786885
585
65695
K510
D
N
L
R
S
R
R
K
M
R
S
Q
S
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
92.5
N.A.
86.5
83.6
N.A.
39.1
27.8
40.2
38.7
N.A.
N.A.
25.9
22.9
28.3
Protein Similarity:
100
99.6
98.5
95.7
N.A.
90.9
89.1
N.A.
56.4
43.2
57.1
54
N.A.
N.A.
46
40.5
43.9
P-Site Identity:
100
93.3
100
86.6
N.A.
93.3
13.3
N.A.
0
6.6
13.3
6.6
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
13.3
13.3
13.3
N.A.
N.A.
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
39
8
0
0
0
24
0
47
8
0
31
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
31
8
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
8
16
31
8
8
0
0
8
0
8
% E
% Phe:
24
0
0
0
0
0
39
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
8
16
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
16
0
0
0
8
8
0
0
% K
% Leu:
0
24
16
47
8
0
0
0
0
8
0
0
47
24
0
% L
% Met:
0
0
0
0
0
39
8
0
8
0
0
0
0
8
0
% M
% Asn:
0
8
0
0
0
0
8
0
8
0
0
0
0
0
24
% N
% Pro:
47
47
16
0
16
0
0
0
8
0
54
16
8
47
0
% P
% Gln:
8
0
0
0
16
16
0
0
0
39
16
8
0
0
0
% Q
% Arg:
0
0
0
8
0
16
16
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
0
8
16
0
8
24
0
16
16
8
0
31
% S
% Thr:
0
0
0
0
0
0
8
39
16
0
0
0
0
0
0
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
39
8
0
0
0
0
0
0
0
0
8
24
0
% W
% Tyr:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _