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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN
All Species:
12.12
Human Site:
S543
Identified Species:
22.22
UniProt:
Q9BST9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BST9
NP_001015055.1
563
62667
S543
A
P
L
P
P
Q
R
S
P
R
T
R
G
L
C
Chimpanzee
Pan troglodytes
XP_001157465
563
62576
S543
A
P
L
P
P
Q
R
S
P
R
T
R
G
L
C
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
S543
A
P
L
P
P
Q
R
S
P
R
T
R
G
L
C
Dog
Lupus familis
XP_532998
564
62928
R543
V
A
P
L
P
Q
Q
R
S
P
R
S
R
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C6B2
564
63022
R543
V
A
P
L
P
P
Q
R
S
P
K
S
R
G
F
Rat
Rattus norvegicus
Q6V7V2
548
61135
P529
P
L
P
P
Q
R
S
P
Q
S
R
G
F
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
A586
S
E
A
K
P
V
P
A
P
R
Q
K
T
L
K
Chicken
Gallus gallus
XP_421541
873
96370
A784
A
K
A
C
G
N
I
A
E
L
D
K
E
N
W
Frog
Xenopus laevis
Q5XGX5
612
69089
K519
P
N
K
T
P
F
S
K
L
V
E
G
N
D
P
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
F540
P
P
P
D
K
L
P
F
T
S
V
S
T
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393113
433
50447
Y414
N
K
R
Q
K
S
L
Y
D
E
T
S
L
L
D
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
S496
Q
Y
K
D
G
K
K
S
W
S
K
S
I
G
S
Sea Urchin
Strong. purpuratus
XP_786885
585
65695
S566
S
S
A
I
S
S
S
S
T
Q
S
P
P
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
92.5
N.A.
86.5
83.6
N.A.
39.1
27.8
40.2
38.7
N.A.
N.A.
25.9
22.9
28.3
Protein Similarity:
100
99.6
98.5
95.7
N.A.
90.9
89.1
N.A.
56.4
43.2
57.1
54
N.A.
N.A.
46
40.5
43.9
P-Site Identity:
100
100
100
13.3
N.A.
6.6
6.6
N.A.
26.6
6.6
6.6
6.6
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
100
100
100
20
N.A.
13.3
13.3
N.A.
46.6
20
6.6
6.6
N.A.
N.A.
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
16
24
0
0
0
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
24
% C
% Asp:
0
0
0
16
0
0
0
0
8
0
8
0
0
8
8
% D
% Glu:
0
8
0
0
0
0
0
0
8
8
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
16
% F
% Gly:
0
0
0
0
16
0
0
0
0
0
0
16
24
24
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
16
16
8
16
8
8
8
0
0
16
16
0
0
8
% K
% Leu:
0
8
24
16
0
8
8
0
8
8
0
0
8
47
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
8
0
0
0
0
0
0
8
16
0
% N
% Pro:
24
31
31
31
54
8
16
8
31
16
0
8
8
0
8
% P
% Gln:
8
0
0
8
8
31
16
0
8
8
8
0
0
0
8
% Q
% Arg:
0
0
8
0
0
8
24
16
0
31
16
24
16
0
0
% R
% Ser:
16
8
0
0
8
16
24
39
16
24
8
39
0
0
16
% S
% Thr:
0
0
0
8
0
0
0
0
16
0
31
0
16
0
0
% T
% Val:
16
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _