KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN
All Species:
13.64
Human Site:
S529
Identified Species:
25
UniProt:
Q9BST9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BST9
NP_001015055.1
563
62667
S529
D
A
V
P
P
D
H
S
P
R
A
R
S
V
A
Chimpanzee
Pan troglodytes
XP_001157465
563
62576
S529
D
A
V
P
P
D
H
S
P
R
A
R
S
V
A
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
F529
D
A
V
P
P
D
H
F
P
R
A
R
S
V
A
Dog
Lupus familis
XP_532998
564
62928
S529
D
A
V
P
P
D
H
S
P
R
A
S
H
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C6B2
564
63022
S529
D
A
A
P
A
D
H
S
L
G
P
S
R
S
V
Rat
Rattus norvegicus
Q6V7V2
548
61135
G515
V
P
A
D
H
S
L
G
P
S
R
S
V
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
T572
E
N
M
M
T
S
G
T
G
I
T
K
A
D
S
Chicken
Gallus gallus
XP_421541
873
96370
S770
R
R
A
P
P
P
P
S
D
K
P
A
Y
N
A
Frog
Xenopus laevis
Q5XGX5
612
69089
R505
S
N
V
K
A
K
K
R
R
A
P
P
P
P
P
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
K526
S
P
D
T
G
S
K
K
K
R
R
A
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393113
433
50447
K400
L
N
E
N
T
N
I
K
N
F
F
N
N
T
N
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
Y482
S
P
R
P
P
S
S
Y
R
H
H
S
D
D
Q
Sea Urchin
Strong. purpuratus
XP_786885
585
65695
P552
L
P
A
A
E
S
S
P
S
T
S
S
P
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
92.5
N.A.
86.5
83.6
N.A.
39.1
27.8
40.2
38.7
N.A.
N.A.
25.9
22.9
28.3
Protein Similarity:
100
99.6
98.5
95.7
N.A.
90.9
89.1
N.A.
56.4
43.2
57.1
54
N.A.
N.A.
46
40.5
43.9
P-Site Identity:
100
100
93.3
73.3
N.A.
40
6.6
N.A.
0
26.6
6.6
6.6
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
40
6.6
N.A.
40
33.3
6.6
6.6
N.A.
N.A.
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
31
8
16
0
0
0
0
8
31
16
8
16
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
8
8
0
39
0
0
8
0
0
0
8
16
0
% D
% Glu:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
8
8
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
39
0
0
8
8
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
16
16
8
8
0
8
0
0
0
% K
% Leu:
16
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
0
8
0
8
0
0
8
0
0
8
8
8
8
% N
% Pro:
0
31
0
54
47
8
8
8
39
0
24
8
24
16
24
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
8
8
8
0
0
0
0
8
16
39
16
24
8
0
0
% R
% Ser:
24
0
0
0
0
39
16
39
8
8
8
39
24
8
16
% S
% Thr:
0
0
0
8
16
0
0
8
0
8
8
0
0
16
0
% T
% Val:
8
0
39
0
0
0
0
0
0
0
0
0
8
24
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _