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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN
All Species:
13.03
Human Site:
S406
Identified Species:
23.89
UniProt:
Q9BST9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BST9
NP_001015055.1
563
62667
S406
E
S
R
E
A
L
Q
S
W
M
E
A
L
W
Q
Chimpanzee
Pan troglodytes
XP_001157465
563
62576
S406
E
S
R
E
A
L
Q
S
W
M
E
A
L
W
Q
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
S406
E
S
R
E
A
L
Q
S
W
M
E
A
L
W
Q
Dog
Lupus familis
XP_532998
564
62928
S406
E
S
R
G
A
L
H
S
W
M
E
A
L
W
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C6B2
564
63022
N406
E
S
R
E
A
L
Q
N
W
M
E
A
L
W
Q
Rat
Rattus norvegicus
Q6V7V2
548
61135
Q392
V
Q
S
R
D
A
L
Q
S
W
M
E
A
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
E449
Q
F
L
I
G
Q
Q
E
E
S
A
T
P
P
W
Chicken
Gallus gallus
XP_421541
873
96370
K647
D
S
R
E
E
L
H
K
W
M
E
A
F
W
Q
Frog
Xenopus laevis
Q5XGX5
612
69089
K382
D
C
K
E
E
L
Q
K
W
M
E
A
F
W
Q
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
E403
E
S
P
D
V
L
Q
E
W
L
D
S
L
W
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393113
433
50447
I277
L
N
N
F
G
N
K
I
Q
I
L
P
L
F
G
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
L359
A
T
K
I
S
S
L
L
T
Q
K
R
E
D
P
Sea Urchin
Strong. purpuratus
XP_786885
585
65695
E429
P
F
M
A
E
S
E
E
E
L
E
M
W
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
92.5
N.A.
86.5
83.6
N.A.
39.1
27.8
40.2
38.7
N.A.
N.A.
25.9
22.9
28.3
Protein Similarity:
100
99.6
98.5
95.7
N.A.
90.9
89.1
N.A.
56.4
43.2
57.1
54
N.A.
N.A.
46
40.5
43.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
0
N.A.
6.6
66.6
60
53.3
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
0
N.A.
13.3
73.3
73.3
80
N.A.
N.A.
33.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
39
8
0
0
0
0
8
54
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
47
0
0
47
24
0
8
24
16
0
62
8
8
0
0
% E
% Phe:
0
16
0
8
0
0
0
0
0
0
0
0
16
8
0
% F
% Gly:
0
0
0
8
16
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
0
8
16
0
0
8
0
0
0
8
% K
% Leu:
8
0
8
0
0
62
16
8
0
16
8
0
54
16
0
% L
% Met:
0
0
8
0
0
0
0
0
0
54
8
8
0
0
0
% M
% Asn:
0
8
8
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
8
8
8
8
% P
% Gln:
8
8
0
0
0
8
54
8
8
8
0
0
0
0
62
% Q
% Arg:
0
0
47
8
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
54
8
0
8
16
0
31
8
8
0
8
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
62
8
0
0
8
62
16
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _