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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RTKN All Species: 23.33
Human Site: S239 Identified Species: 42.78
UniProt: Q9BST9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BST9 NP_001015055.1 563 62667 S239 S L D S A G G S G S S P I L L
Chimpanzee Pan troglodytes XP_001157465 563 62576 S239 S L D S A G G S G S S P I L L
Rhesus Macaque Macaca mulatta XP_001108982 563 62606 S239 S L D S A G G S G S S P I L L
Dog Lupus familis XP_532998 564 62928 S239 S L E S A G G S G S S P I L L
Cat Felis silvestris
Mouse Mus musculus Q8C6B2 564 63022 S239 S L D S A G A S G N S P V L L
Rat Rattus norvegicus Q6V7V2 548 61135 S226 S L D S A G G S G N S P I L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510217 606 68399 E247 S L A I T G N E E S S F W L P
Chicken Gallus gallus XP_421541 873 96370 D480 L K A T L E D D G T D S I L L
Frog Xenopus laevis Q5XGX5 612 69089 E218 E L E A T E P E A F L F S T P
Zebra Danio Brachydanio rerio Q5XIZ9 642 72394 G236 L C P L L D G G D P D T F L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393113 433 50447 S117 L K T S T F N S K G K L S I S
Nematode Worm Caenorhab. elegans NP_001024370 515 57305 D200 K A T L S I A D A C E E A T I
Sea Urchin Strong. purpuratus XP_786885 585 65695 V269 S L G H R T Q V N S T S G S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.2 92.5 N.A. 86.5 83.6 N.A. 39.1 27.8 40.2 38.7 N.A. N.A. 25.9 22.9 28.3
Protein Similarity: 100 99.6 98.5 95.7 N.A. 90.9 89.1 N.A. 56.4 43.2 57.1 54 N.A. N.A. 46 40.5 43.9
P-Site Identity: 100 100 100 93.3 N.A. 80 93.3 N.A. 40 26.6 6.6 13.3 N.A. N.A. 13.3 0 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 40 40 20 13.3 N.A. N.A. 20 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 8 47 0 16 0 16 0 0 0 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 39 0 0 8 8 16 8 0 16 0 0 0 0 % D
% Glu: 8 0 16 0 0 16 0 16 8 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 8 0 16 8 0 0 % F
% Gly: 0 0 8 0 0 54 47 8 54 8 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 0 0 47 8 8 % I
% Lys: 8 16 0 0 0 0 0 0 8 0 8 0 0 0 0 % K
% Leu: 24 70 0 16 16 0 0 0 0 0 8 8 0 70 54 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 16 0 8 16 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 0 8 0 0 8 0 47 0 0 16 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 62 0 0 54 8 0 0 54 0 47 54 16 16 8 8 % S
% Thr: 0 0 16 8 24 8 0 0 0 8 8 8 0 16 8 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _