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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RTKN All Species: 23.33
Human Site: S219 Identified Species: 42.78
UniProt: Q9BST9 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BST9 NP_001015055.1 563 62667 S219 R L A T K L S S S L G R S S G
Chimpanzee Pan troglodytes XP_001157465 563 62576 S219 R L A T K L S S S L G R S S G
Rhesus Macaque Macaca mulatta XP_001108982 563 62606 S219 R L A T K L S S S L G R S S G
Dog Lupus familis XP_532998 564 62928 S219 R L A T K L S S S L G R S S G
Cat Felis silvestris
Mouse Mus musculus Q8C6B2 564 63022 S219 R L A T K L S S S L G R S S G
Rat Rattus norvegicus Q6V7V2 548 61135 S206 R L A T K L S S S L G R S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510217 606 68399 L227 H L L A H T T L T L E S T E D
Chicken Gallus gallus XP_421541 873 96370 K460 T P K K L V K K L K T S L S K
Frog Xenopus laevis Q5XGX5 612 69089 N198 K L A R K L R N S I G K S A G
Zebra Danio Brachydanio rerio Q5XIZ9 642 72394 K216 T P K K L A R K L R S S F G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393113 433 50447 Y97 S S K R M S A Y M V E L E H Q
Nematode Worm Caenorhab. elegans NP_001024370 515 57305 D180 M L K S P R L D Q T I S G A H
Sea Urchin Strong. purpuratus XP_786885 585 65695 K249 T P Q K I R R K L S A L S A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.2 92.5 N.A. 86.5 83.6 N.A. 39.1 27.8 40.2 38.7 N.A. N.A. 25.9 22.9 28.3
Protein Similarity: 100 99.6 98.5 95.7 N.A. 90.9 89.1 N.A. 56.4 43.2 57.1 54 N.A. N.A. 46 40.5 43.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 6.6 53.3 0 N.A. N.A. 0 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 13.3 86.6 0 N.A. N.A. 13.3 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 54 8 0 8 8 0 0 0 8 0 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 16 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 54 0 8 8 54 % G
% His: 8 0 0 0 8 0 0 0 0 0 0 0 0 8 8 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 8 0 0 0 0 % I
% Lys: 8 0 31 24 54 0 8 24 0 8 0 8 0 0 8 % K
% Leu: 0 70 8 0 16 54 8 8 24 54 0 16 8 0 0 % L
% Met: 8 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 24 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 47 0 0 16 0 16 24 0 0 8 0 47 0 0 8 % R
% Ser: 8 8 0 8 0 8 47 47 54 8 8 31 62 54 8 % S
% Thr: 24 0 0 47 0 8 8 0 8 8 8 0 8 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _