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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESYT1
All Species:
24.55
Human Site:
Y518
Identified Species:
49.09
UniProt:
Q9BSJ8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSJ8
NP_056107.1
1104
122856
Y518
T
Q
E
S
K
A
V
Y
S
T
N
C
P
V
W
Chimpanzee
Pan troglodytes
XP_509135
1104
122804
Y518
T
Q
E
S
K
A
V
Y
S
T
N
C
P
V
W
Rhesus Macaque
Macaca mulatta
XP_001114269
1104
122642
Y518
T
Q
E
S
K
A
V
Y
S
T
N
C
P
V
W
Dog
Lupus familis
XP_531630
1118
122912
Y531
T
Q
E
S
K
A
V
Y
C
T
N
S
P
V
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7R1
1092
121535
Y508
T
R
E
S
K
A
T
Y
S
T
N
S
P
V
W
Rat
Rattus norvegicus
Q9Z1X1
1088
121141
Y510
T
Q
E
S
K
A
T
Y
S
T
N
C
P
V
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510769
598
67043
K60
G
T
F
P
D
V
E
K
V
E
W
L
N
K
I
Chicken
Gallus gallus
XP_001233946
754
85084
R216
P
I
P
K
G
V
L
R
I
H
F
I
E
A
Q
Frog
Xenopus laevis
Q5FWL4
872
98061
G334
W
K
D
T
Y
M
K
G
L
V
K
G
K
S
D
Zebra Danio
Brachydanio rerio
XP_695611
1079
121013
Y505
T
K
E
S
R
T
V
Y
G
T
N
N
P
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733011
849
94440
R311
P
G
L
S
D
L
L
R
R
I
I
V
E
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183287
830
92887
P292
R
P
L
V
N
K
M
P
L
I
G
G
M
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.8
81.6
N.A.
87.3
86.6
N.A.
43.9
34.5
34.8
52.9
N.A.
26.1
N.A.
N.A.
23.1
Protein Similarity:
100
99.6
98.9
87.6
N.A.
92.6
92.3
N.A.
49.7
50.8
52.9
72.6
N.A.
42.2
N.A.
N.A.
40
P-Site Identity:
100
100
100
86.6
N.A.
80
93.3
N.A.
0
0
0
60
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
0
6.6
20
73.3
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
34
0
0
0
% C
% Asp:
0
0
9
0
17
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
59
0
0
0
9
0
0
9
0
0
17
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
9
0
0
9
0
0
9
9
0
9
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
9
17
9
9
0
0
25
% I
% Lys:
0
17
0
9
50
9
9
9
0
0
9
0
9
9
0
% K
% Leu:
0
0
17
0
0
9
17
0
17
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
9
9
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
59
9
9
0
0
% N
% Pro:
17
9
9
9
0
0
0
9
0
0
0
0
59
0
0
% P
% Gln:
0
42
0
0
0
0
0
0
0
0
0
0
0
9
9
% Q
% Arg:
9
9
0
0
9
0
0
17
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
67
0
0
0
0
42
0
0
17
0
17
0
% S
% Thr:
59
9
0
9
0
9
17
0
0
59
0
0
0
0
0
% T
% Val:
0
0
0
9
0
17
42
0
9
9
0
9
0
50
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
59
% W
% Tyr:
0
0
0
0
9
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _