KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESYT1
All Species:
19.7
Human Site:
T178
Identified Species:
39.39
UniProt:
Q9BSJ8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSJ8
NP_056107.1
1104
122856
T178
G
S
N
P
H
L
Q
T
F
T
F
T
R
V
E
Chimpanzee
Pan troglodytes
XP_509135
1104
122804
T178
G
S
N
P
H
L
Q
T
F
T
F
T
R
V
E
Rhesus Macaque
Macaca mulatta
XP_001114269
1104
122642
T178
G
S
N
P
H
L
Q
T
F
T
F
T
R
V
E
Dog
Lupus familis
XP_531630
1118
122912
D195
G
A
R
T
A
Q
R
D
R
T
S
G
N
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7R1
1092
121535
T168
G
A
N
P
H
L
Q
T
F
T
F
T
R
V
E
Rat
Rattus norvegicus
Q9Z1X1
1088
121141
T170
G
A
N
P
H
L
Q
T
F
T
F
T
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510769
598
67043
Chicken
Gallus gallus
XP_001233946
754
85084
Frog
Xenopus laevis
Q5FWL4
872
98061
R87
N
K
G
N
K
N
S
R
L
Y
R
A
L
A
F
Zebra Danio
Brachydanio rerio
XP_695611
1079
121013
A174
K
V
D
L
G
D
R
A
M
K
V
V
G
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733011
849
94440
T64
N
G
N
S
I
V
A
T
K
S
V
S
D
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001183287
830
92887
K45
L
D
L
A
P
R
W
K
A
S
T
D
A
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.8
81.6
N.A.
87.3
86.6
N.A.
43.9
34.5
34.8
52.9
N.A.
26.1
N.A.
N.A.
23.1
Protein Similarity:
100
99.6
98.9
87.6
N.A.
92.6
92.3
N.A.
49.7
50.8
52.9
72.6
N.A.
42.2
N.A.
N.A.
40
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
0
0
0
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
0
0
0
26.6
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
9
9
0
9
9
9
0
0
9
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
9
0
9
0
0
0
9
9
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
42
0
42
0
0
0
9
% F
% Gly:
50
9
9
0
9
0
0
0
0
0
0
9
9
0
0
% G
% His:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
0
0
9
9
9
0
0
0
0
9
% K
% Leu:
9
0
9
9
0
42
0
0
9
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
17
0
50
9
0
9
0
0
0
0
0
0
9
0
9
% N
% Pro:
0
0
0
42
9
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
9
42
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
9
0
0
9
17
9
9
0
9
0
42
0
0
% R
% Ser:
0
25
0
9
0
0
9
0
0
17
9
9
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
50
0
50
9
42
0
0
0
% T
% Val:
0
9
0
0
0
9
0
0
0
0
17
9
0
50
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _