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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK1
All Species:
30.3
Human Site:
S504
Identified Species:
51.28
UniProt:
Q9BRS2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRS2
NP_113668.2
568
65583
S504
D
S
E
D
I
G
S
S
E
C
S
D
T
D
S
Chimpanzee
Pan troglodytes
XP_527225
568
65487
S504
D
S
E
D
T
G
S
S
E
C
S
D
T
D
S
Rhesus Macaque
Macaca mulatta
XP_001084661
567
65490
S503
D
S
E
D
T
G
S
S
E
C
S
D
T
D
S
Dog
Lupus familis
XP_535878
569
65688
S505
D
S
Q
D
A
G
S
S
E
C
S
D
T
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q2
567
64892
S503
G
S
D
D
A
G
G
S
E
C
S
D
T
V
S
Rat
Rattus norvegicus
XP_214454
566
65166
S502
D
S
D
D
A
G
S
S
E
C
S
D
T
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514154
620
71362
S556
H
S
E
D
D
D
S
S
D
S
S
D
S
D
F
Chicken
Gallus gallus
XP_418958
569
65247
S508
D
D
D
D
G
G
S
S
E
D
S
D
S
S
C
Frog
Xenopus laevis
NP_001116165
542
62486
D478
S
D
D
D
D
D
N
D
D
G
A
K
D
S
A
Zebra Danio
Brachydanio rerio
NP_998160
552
63898
E502
E
E
E
D
E
D
D
E
E
K
S
G
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648489
585
67475
D526
E
D
E
D
N
S
Q
D
N
D
N
D
E
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793660
539
63109
S485
E
E
D
E
E
K
T
S
E
R
Q
H
H
R
P
Poplar Tree
Populus trichocarpa
XP_002322256
559
63327
S501
E
E
E
G
S
G
D
S
D
G
S
G
S
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12196
484
56104
K442
P
K
V
L
K
G
K
K
H
E
D
K
D
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.5
89.6
N.A.
80.2
81.5
N.A.
73
75.2
70.4
69.7
N.A.
47
N.A.
N.A.
50.1
Protein Similarity:
100
98.9
96.8
94.9
N.A.
88
89.7
N.A.
80.9
84.1
80.6
82.2
N.A.
64.2
N.A.
N.A.
66
P-Site Identity:
100
93.3
93.3
86.6
N.A.
66.6
80
N.A.
53.3
53.3
6.6
26.6
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
73.3
86.6
N.A.
66.6
66.6
40
46.6
N.A.
46.6
N.A.
N.A.
40
Percent
Protein Identity:
41
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
60.7
N.A.
N.A.
N.A.
49.3
N.A.
P-Site Identity:
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
22
0
0
0
0
0
8
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
43
0
0
0
0
8
% C
% Asp:
43
22
36
79
15
22
15
15
22
15
8
65
15
50
0
% D
% Glu:
29
22
50
8
15
0
0
8
65
8
0
0
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
8
8
65
8
0
0
15
0
15
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
8
8
8
0
8
0
15
0
0
8
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
8
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
8
50
0
0
8
8
50
72
0
8
72
0
22
22
43
% S
% Thr:
0
0
0
0
15
0
8
0
0
0
0
0
43
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _