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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM2
All Species:
17.58
Human Site:
Y223
Identified Species:
35.15
UniProt:
Q9BRQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ8
NP_116186.1
373
40527
Y223
P
L
N
E
Y
R
E
Y
I
K
V
Q
T
D
K
Chimpanzee
Pan troglodytes
XP_001170630
373
40520
Y223
P
L
N
E
Y
R
E
Y
I
K
V
Q
T
D
K
Rhesus Macaque
Macaca mulatta
XP_001108666
373
40507
Y223
P
L
N
E
Y
R
E
Y
I
K
V
Q
T
D
K
Dog
Lupus familis
XP_536378
373
40566
R223
P
L
N
E
Y
R
E
R
I
Q
V
H
T
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE4
373
40616
Y223
P
R
N
E
Y
R
E
Y
I
K
V
E
T
D
K
Rat
Rattus norvegicus
NP_001132955
373
40672
Y223
P
R
N
E
Y
R
E
Y
I
K
V
E
T
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421597
373
40601
D222
T
T
N
Q
F
Q
K
D
M
V
V
R
T
E
K
Frog
Xenopus laevis
Q6GLW8
374
40759
M223
P
N
V
A
Q
E
N
M
E
L
Q
L
D
K
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781398
553
60494
G220
D
I
P
R
D
L
S
G
A
T
V
L
T
D
K
Poplar Tree
Populus trichocarpa
XP_002299779
362
39920
K209
V
T
D
S
N
G
S
K
I
Y
H
T
T
A
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXR9
519
56898
A334
Y
F
L
E
L
Q
P
A
E
R
G
L
E
S
Q
Baker's Yeast
Sacchar. cerevisiae
P32340
513
57231
E321
L
L
A
K
T
K
H
E
D
G
K
I
T
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
85.5
N.A.
90.3
90.6
N.A.
N.A.
69.7
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
99.7
99.1
94
N.A.
96.2
96.7
N.A.
N.A.
86
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
73.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
31.3
N.A.
N.A.
22.1
23
N.A.
Protein Similarity:
51.2
N.A.
N.A.
37.3
38.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
9
9
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
0
9
0
0
9
9
0
0
0
9
59
9
% D
% Glu:
0
0
0
59
0
9
50
9
17
0
0
17
9
17
9
% E
% Phe:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
9
0
9
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
59
0
0
9
0
0
0
% I
% Lys:
0
0
0
9
0
9
9
9
0
42
9
0
0
9
67
% K
% Leu:
9
42
9
0
9
9
0
0
0
9
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
9
59
0
9
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
59
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
9
17
0
0
0
9
9
25
0
0
9
% Q
% Arg:
0
17
0
9
0
50
0
9
0
9
0
9
0
0
0
% R
% Ser:
0
0
0
9
0
0
17
0
0
0
0
0
0
9
0
% S
% Thr:
9
17
0
0
9
0
0
0
0
9
0
9
84
0
0
% T
% Val:
9
0
9
0
0
0
0
0
0
9
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
50
0
0
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _