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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM2
All Species:
28.18
Human Site:
S206
Identified Species:
56.36
UniProt:
Q9BRQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ8
NP_116186.1
373
40527
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Chimpanzee
Pan troglodytes
XP_001170630
373
40520
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Rhesus Macaque
Macaca mulatta
XP_001108666
373
40507
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Dog
Lupus familis
XP_536378
373
40566
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE4
373
40616
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Rat
Rattus norvegicus
NP_001132955
373
40672
S206
K
G
V
Q
L
L
L
S
E
R
V
S
N
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421597
373
40601
S205
K
G
V
R
L
L
L
S
E
K
V
S
N
V
E
Frog
Xenopus laevis
Q6GLW8
374
40759
Q206
G
V
R
L
I
L
A
Q
K
V
T
N
L
D
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781398
553
60494
V203
E
E
L
N
V
K
L
V
F
G
E
K
V
T
N
Poplar Tree
Populus trichocarpa
XP_002299779
362
39920
K192
T
S
K
R
V
D
V
K
L
E
Q
R
V
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXR9
519
56898
R317
Y
L
V
Q
S
I
K
R
A
S
N
L
E
E
D
Baker's Yeast
Sacchar. cerevisiae
P32340
513
57231
T304
S
I
K
V
H
L
R
T
A
V
A
K
V
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
85.5
N.A.
90.3
90.6
N.A.
N.A.
69.7
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
99.7
99.1
94
N.A.
96.2
96.7
N.A.
N.A.
86
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
31.3
N.A.
N.A.
22.1
23
N.A.
Protein Similarity:
51.2
N.A.
N.A.
37.3
38.7
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
17
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
9
% D
% Glu:
9
9
0
0
0
0
0
0
59
9
9
0
9
17
67
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
59
0
0
0
0
0
0
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
17
0
0
9
9
9
9
9
0
17
0
0
0
% K
% Leu:
0
9
9
9
59
75
67
0
9
0
0
9
9
50
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
9
59
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
59
0
0
0
9
0
0
9
0
0
0
9
% Q
% Arg:
0
0
9
17
0
0
9
9
0
50
0
9
0
0
0
% R
% Ser:
9
9
0
0
9
0
0
59
0
9
0
59
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
0
9
0
0
9
0
% T
% Val:
0
9
67
9
17
0
9
9
0
17
59
0
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _