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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AIFM2 All Species: 18.48
Human Site: S187 Identified Species: 36.97
UniProt: Q9BRQ8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ8 NP_116186.1 373 40527 S187 A D K E L L P S V R Q E V K E
Chimpanzee Pan troglodytes XP_001170630 373 40520 S187 A D K E L L P S V R Q E V R E
Rhesus Macaque Macaca mulatta XP_001108666 373 40507 S187 A D K E L L P S V R Q E V K E
Dog Lupus familis XP_536378 373 40566 C187 A D K E L L P C V R Q E A K E
Cat Felis silvestris
Mouse Mus musculus Q8BUE4 373 40616 C187 A D K E L L P C V R Q E V K E
Rat Rattus norvegicus NP_001132955 373 40672 C187 A D K E L L P C V R Q E V K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421597 373 40601 S186 A D V E L L Q S V R Q E V K E
Frog Xenopus laevis Q6GLW8 374 40759 S186 A D V Q L Q P S V R R T V K E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781398 553 60494 T186 V E P A T S D T F R A S V Q K
Poplar Tree Populus trichocarpa XP_002299779 362 39920 A176 L E F I G P K A S D K T L Q W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXR9 519 56898 N278 R G I V Q S I N V S K N I L T
Baker's Yeast Sacchar. cerevisiae P32340 513 57231 A273 V Q I H L V E A L P I V L N M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.3 85.5 N.A. 90.3 90.6 N.A. N.A. 69.7 61.5 N.A. N.A. N.A. N.A. N.A. 27.8
Protein Similarity: 100 99.7 99.1 94 N.A. 96.2 96.7 N.A. N.A. 86 81.8 N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: 100 93.3 100 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 66.6 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 86.6 80 N.A. N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 31.3 N.A. N.A. 22.1 23 N.A.
Protein Similarity: 51.2 N.A. N.A. 37.3 38.7 N.A.
P-Site Identity: 0 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 9 0 0 0 17 0 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 % C
% Asp: 0 67 0 0 0 0 9 0 0 9 0 0 0 0 0 % D
% Glu: 0 17 0 59 0 0 9 0 0 0 0 59 0 0 67 % E
% Phe: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 17 9 0 0 9 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 50 0 0 0 9 0 0 0 17 0 0 59 9 % K
% Leu: 9 0 0 0 75 59 0 0 9 0 0 0 17 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 9 0 9 0 % N
% Pro: 0 0 9 0 0 9 59 0 0 9 0 0 0 0 0 % P
% Gln: 0 9 0 9 9 9 9 0 0 0 59 0 0 17 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 75 9 0 0 9 0 % R
% Ser: 0 0 0 0 0 17 0 42 9 9 0 9 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 9 0 0 0 17 0 0 9 % T
% Val: 17 0 17 9 0 9 0 0 75 0 0 9 67 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _