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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM2
All Species:
33.33
Human Site:
S175
Identified Species:
66.67
UniProt:
Q9BRQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ8
NP_116186.1
373
40527
S175
K
E
V
T
L
I
H
S
Q
V
A
L
A
D
K
Chimpanzee
Pan troglodytes
XP_001170630
373
40520
S175
K
E
V
T
L
I
H
S
Q
V
A
L
A
D
K
Rhesus Macaque
Macaca mulatta
XP_001108666
373
40507
S175
K
E
V
T
L
I
H
S
Q
V
A
L
A
D
K
Dog
Lupus familis
XP_536378
373
40566
S175
K
E
V
T
L
I
H
S
Q
V
A
L
A
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE4
373
40616
S175
K
E
V
T
L
I
H
S
R
V
P
L
A
D
K
Rat
Rattus norvegicus
NP_001132955
373
40672
S175
K
E
V
T
L
I
H
S
R
V
P
L
A
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421597
373
40601
S174
K
E
V
T
L
I
H
S
K
I
A
L
A
D
V
Frog
Xenopus laevis
Q6GLW8
374
40759
S174
K
E
V
T
L
I
H
S
K
I
A
L
A
D
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781398
553
60494
A174
K
E
V
T
I
I
H
A
R
D
S
L
V
E
P
Poplar Tree
Populus trichocarpa
XP_002299779
362
39920
S164
K
H
V
T
L
V
H
S
G
S
R
L
L
E
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXR9
519
56898
E266
E
L
A
A
T
I
S
E
R
L
Q
D
R
G
I
Baker's Yeast
Sacchar. cerevisiae
P32340
513
57231
A261
D
L
R
K
F
L
P
A
L
A
E
E
V
Q
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
85.5
N.A.
90.3
90.6
N.A.
N.A.
69.7
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
99.7
99.1
94
N.A.
96.2
96.7
N.A.
N.A.
86
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
31.3
N.A.
N.A.
22.1
23
N.A.
Protein Similarity:
51.2
N.A.
N.A.
37.3
38.7
N.A.
P-Site Identity:
46.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
60
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
17
0
9
50
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
9
0
9
0
67
0
% D
% Glu:
9
75
0
0
0
0
0
9
0
0
9
9
0
17
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% G
% His:
0
9
0
0
0
0
84
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
84
0
0
0
17
0
0
0
0
17
% I
% Lys:
84
0
0
9
0
0
0
0
17
0
0
0
0
0
50
% K
% Leu:
0
17
0
0
75
9
0
0
9
9
0
84
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
17
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
9
0
0
9
0
% Q
% Arg:
0
0
9
0
0
0
0
0
34
0
9
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
9
75
0
9
9
0
0
0
0
% S
% Thr:
0
0
0
84
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
84
0
0
9
0
0
0
50
0
0
17
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _