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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22C
All Species:
8.79
Human Site:
S59
Identified Species:
17.58
UniProt:
Q9BRL7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRL7
NP_004197.1
303
34269
S59
S
A
E
G
C
D
F
S
I
H
F
S
S
F
G
Chimpanzee
Pan troglodytes
XP_001139515
303
34283
S59
S
A
E
G
C
D
F
S
I
H
F
S
S
F
G
Rhesus Macaque
Macaca mulatta
XP_001115333
303
34463
S59
S
A
E
G
R
D
F
S
I
H
F
S
S
F
G
Dog
Lupus familis
XP_850413
303
34347
N59
S
A
E
G
C
D
F
N
I
H
F
S
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXT9
303
33895
L59
C
A
E
S
C
D
F
L
I
Y
F
S
S
S
G
Rat
Rattus norvegicus
Q642F4
307
34883
N59
T
L
K
T
G
R
H
N
I
N
F
I
S
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509142
224
24689
R8
F
A
C
V
V
R
V
R
D
G
L
P
L
S
A
Chicken
Gallus gallus
Q5ZJW4
215
24699
Frog
Xenopus laevis
NP_001087747
293
32527
N59
T
A
K
V
F
D
F
N
I
H
F
C
S
S
A
Zebra Danio
Brachydanio rerio
Q7ZV15
215
24372
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
W60
S
M
F
T
G
S
H
W
L
Y
F
I
S
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97
90.7
N.A.
81.5
40
N.A.
42.9
23.1
52.4
22.7
N.A.
N.A.
N.A.
N.A.
30.1
Protein Similarity:
100
100
98
96.6
N.A.
91
57.3
N.A.
51.4
36.9
71.9
37.6
N.A.
N.A.
N.A.
N.A.
49
P-Site Identity:
100
100
93.3
80
N.A.
66.6
20
N.A.
6.6
0
46.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
46.6
N.A.
6.6
0
66.6
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
17
% A
% Cys:
9
0
9
0
34
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
50
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
0
9
0
50
0
0
0
67
0
0
25
0
% F
% Gly:
0
0
0
34
17
0
0
0
0
9
0
0
0
0
34
% G
% His:
0
0
0
0
0
0
17
0
0
42
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
59
0
0
17
0
0
0
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
9
9
0
9
0
9
9
17
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
17
0
9
0
0
0
0
0
0
9
% R
% Ser:
42
0
0
9
0
9
0
25
0
0
0
42
67
42
0
% S
% Thr:
17
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
17
9
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _