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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
23.94
Human Site:
Y706
Identified Species:
40.51
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
Y706
L
R
F
V
V
M
D
Y
D
W
K
S
R
N
D
Chimpanzee
Pan troglodytes
XP_526029
762
87514
Y706
L
R
F
V
V
M
D
Y
D
W
K
S
R
N
D
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
Y743
L
R
F
V
V
M
D
Y
D
W
K
S
R
N
D
Dog
Lupus familis
XP_536069
769
88595
Y713
L
R
F
V
V
K
D
Y
N
W
K
S
R
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
Y751
L
R
F
V
V
K
D
Y
S
R
K
S
R
N
N
Rat
Rattus norvegicus
Q62711
772
88948
Y716
L
R
F
V
V
K
D
Y
S
R
T
S
R
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
F683
P
E
L
A
L
V
R
F
V
V
D
D
Y
D
I
Chicken
Gallus gallus
Q2VRL0
637
72514
I582
Q
V
P
E
L
A
L
I
R
F
C
V
Q
D
E
Frog
Xenopus laevis
Q32NH8
758
87399
Y701
V
R
F
V
V
E
D
Y
D
K
T
S
R
N
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
H720
V
R
F
M
V
E
D
H
D
H
K
S
K
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
G758
D
L
A
V
L
R
F
G
V
Y
E
E
S
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
L698
P
E
L
A
L
I
R
L
V
V
Q
D
Y
D
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
L529
T
V
P
E
L
A
L
L
R
I
E
V
H
E
Y
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
P801
S
Q
G
N
G
F
N
P
I
W
D
A
E
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
0
0
73.3
60
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
73.3
N.A.
26.6
33.3
80
86.6
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
15
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
58
0
36
0
15
15
0
22
43
% D
% Glu:
0
15
0
15
0
15
0
0
0
0
15
8
8
8
8
% E
% Phe:
0
0
58
0
0
8
8
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
8
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
22
0
0
0
8
43
0
8
0
8
% K
% Leu:
43
8
15
0
36
0
15
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
22
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
8
0
8
0
0
0
0
58
15
% N
% Pro:
15
0
15
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% Q
% Arg:
0
58
0
0
0
8
15
0
15
15
0
0
50
0
0
% R
% Ser:
8
0
0
0
0
0
0
0
15
0
0
58
8
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% T
% Val:
15
15
0
58
58
8
0
0
22
15
0
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
8
0
0
15
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _