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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
23.94
Human Site:
Y518
Identified Species:
40.51
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
Y518
S
K
E
H
Y
H
F
Y
E
I
S
S
F
S
E
Chimpanzee
Pan troglodytes
XP_526029
762
87514
Y518
S
K
E
H
Y
H
F
Y
E
I
S
S
F
S
E
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
Y555
S
K
K
H
Y
H
F
Y
E
I
S
S
F
S
E
Dog
Lupus familis
XP_536069
769
88595
Y525
S
R
E
H
Y
R
F
Y
E
T
S
S
F
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
Y563
S
K
E
N
Y
H
I
Y
D
I
S
S
F
S
E
Rat
Rattus norvegicus
Q62711
772
88948
Y528
S
K
E
N
Y
H
I
Y
D
I
S
S
F
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S501
D
R
P
F
Y
E
M
S
S
L
S
E
N
K
A
Chicken
Gallus gallus
Q2VRL0
637
72514
Q413
S
I
G
E
L
K
A
Q
K
F
V
K
H
A
A
Frog
Xenopus laevis
Q32NH8
758
87399
S514
H
Y
I
L
Y
E
M
S
S
V
T
E
Y
K
A
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
E539
I
T
S
F
S
E
N
E
A
L
K
L
I
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
H575
A
I
E
K
N
I
A
H
N
M
S
S
F
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
G525
C
H
Q
M
S
S
F
G
E
A
K
A
F
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
K360
L
S
E
E
Q
L
E
K
A
S
E
K
Y
A
K
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
F613
S
K
T
I
A
H
C
F
S
L
N
E
R
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
13.3
6.6
6.6
0
N.A.
33.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
26.6
20
26.6
13.3
N.A.
60
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
15
0
15
8
0
8
0
22
22
% A
% Cys:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
8
% D
% Glu:
0
0
50
15
0
22
8
8
36
0
8
22
0
0
50
% E
% Phe:
0
0
0
15
0
0
36
8
0
8
0
0
58
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
8
8
0
29
0
43
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
15
8
8
0
8
15
0
0
36
0
0
8
0
0
% I
% Lys:
0
43
8
8
0
8
0
8
8
0
15
15
0
29
8
% K
% Leu:
8
0
0
8
8
8
0
0
0
22
0
8
0
0
8
% L
% Met:
0
0
0
8
0
0
15
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
15
8
0
8
0
8
0
8
0
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
58
8
8
0
15
8
0
15
22
8
58
50
0
43
0
% S
% Thr:
0
8
8
0
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
58
0
0
43
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _