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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
25.45
Human Site:
Y174
Identified Species:
43.08
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
Y174
N
V
E
M
D
Q
E
Y
A
F
S
L
F
Q
A
Chimpanzee
Pan troglodytes
XP_526029
762
87514
Y174
N
V
E
M
D
Q
E
Y
A
F
S
L
F
Q
A
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
Y174
N
V
E
M
D
Q
E
Y
A
F
S
L
F
Q
A
Dog
Lupus familis
XP_536069
769
88595
Y176
N
V
E
M
D
Q
E
Y
A
F
H
L
F
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
Y174
N
V
E
M
D
E
E
Y
A
F
S
L
F
Q
E
Rat
Rattus norvegicus
Q62711
772
88948
Y174
N
V
E
M
D
E
E
Y
A
F
S
L
F
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
R164
Q
V
D
D
S
Y
A
R
W
I
F
K
E
C
D
Chicken
Gallus gallus
Q2VRL0
637
72514
A81
E
F
H
E
I
F
C
A
Y
S
E
N
R
K
N
Frog
Xenopus laevis
Q32NH8
758
87399
H174
N
V
D
M
S
E
H
H
A
F
R
L
F
Q
M
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y199
N
I
D
L
N
E
Q
Y
A
R
T
L
F
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D194
L
V
Y
T
C
I
K
D
A
G
L
P
D
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
N183
K
R
L
F
Q
F
A
N
T
H
S
T
T
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
K28
S
V
A
P
A
E
I
K
T
L
F
D
N
Y
S
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
P227
L
M
E
S
I
L
L
P
D
N
S
Q
F
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
6.6
0
53.3
33.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
13.3
6.6
73.3
86.6
N.A.
20
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
15
8
65
0
0
0
0
8
22
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
22
8
43
0
0
8
8
0
0
8
8
8
8
% D
% Glu:
8
0
50
8
0
36
43
0
0
0
8
0
8
0
15
% E
% Phe:
0
8
0
8
0
15
0
0
0
50
15
0
65
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
8
8
0
8
8
0
0
0
0
% H
% Ile:
0
8
0
0
15
8
8
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
8
8
0
0
0
8
0
15
22
% K
% Leu:
15
0
8
8
0
8
8
0
0
8
8
58
0
0
0
% L
% Met:
0
8
0
50
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
58
0
0
0
8
0
0
8
0
8
0
8
8
0
8
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
8
29
8
0
0
0
0
8
0
50
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
8
8
0
8
0
8
% R
% Ser:
8
0
0
8
15
0
0
0
0
8
50
0
0
0
8
% S
% Thr:
0
0
0
8
0
0
0
0
15
0
8
8
8
8
8
% T
% Val:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
50
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _