KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
17.88
Human Site:
T127
Identified Species:
30.26
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
T127
Q
L
L
V
D
L
V
T
S
M
D
H
Q
E
R
Chimpanzee
Pan troglodytes
XP_526029
762
87514
T127
Q
L
L
V
D
L
V
T
S
M
D
H
Q
E
R
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
T127
H
L
L
V
D
L
V
T
S
M
D
H
Q
E
R
Dog
Lupus familis
XP_536069
769
88595
M129
L
M
D
F
V
N
G
M
D
Q
Q
E
R
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
A127
Q
L
L
V
D
L
V
A
S
M
D
H
Q
E
Q
Rat
Rattus norvegicus
Q62711
772
88948
A127
Q
L
L
V
D
L
V
A
R
M
N
Y
Q
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
N121
W
S
W
S
L
F
L
N
H
D
T
S
W
I
H
Chicken
Gallus gallus
Q2VRL0
637
72514
L38
K
L
H
M
P
F
N
L
A
H
V
K
H
V
F
Frog
Xenopus laevis
Q32NH8
758
87399
T127
E
K
L
I
E
T
V
T
N
M
D
R
K
D
L
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S152
R
T
L
K
D
R
V
S
N
M
S
Q
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
R143
R
L
I
T
H
N
N
R
A
T
N
V
C
P
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
Q127
R
W
L
K
K
K
S
Q
H
I
D
I
H
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Y184
K
L
W
I
A
I
I
Y
K
V
S
N
K
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
93.3
0
N.A.
86.6
66.6
N.A.
0
6.6
33.3
33.3
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
13.3
N.A.
93.3
86.6
N.A.
6.6
26.6
73.3
66.6
N.A.
40
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
15
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
43
0
0
0
8
8
43
0
0
8
8
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
0
8
0
43
0
% E
% Phe:
0
0
0
8
0
15
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
8
0
8
0
8
0
0
0
15
8
0
29
15
0
8
% H
% Ile:
0
0
8
15
0
8
8
0
0
8
0
8
0
8
0
% I
% Lys:
15
8
0
15
8
8
0
0
8
0
0
8
22
0
22
% K
% Leu:
8
58
58
0
8
36
8
8
0
0
0
0
0
15
8
% L
% Met:
0
8
0
8
0
0
0
8
0
50
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
15
8
15
0
15
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
29
0
0
0
0
0
0
8
0
8
8
8
36
0
15
% Q
% Arg:
22
0
0
0
0
8
0
8
8
0
0
8
8
0
29
% R
% Ser:
0
8
0
8
0
0
8
8
29
0
15
8
0
8
0
% S
% Thr:
0
8
0
8
0
8
0
29
0
8
8
0
0
0
0
% T
% Val:
0
0
0
36
8
0
50
0
0
8
8
8
0
8
0
% V
% Trp:
8
8
15
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _