KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
26.36
Human Site:
S736
Identified Species:
44.62
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S736
Y
R
H
I
H
L
L
S
K
D
G
I
S
L
R
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S736
Y
R
H
I
H
L
L
S
K
D
G
I
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S773
Y
R
H
I
H
L
L
S
K
D
G
I
S
L
C
Dog
Lupus familis
XP_536069
769
88595
S743
Y
R
H
I
H
L
L
S
K
D
G
T
S
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S781
Y
R
H
V
S
L
L
S
R
D
G
T
S
L
N
Rat
Rattus norvegicus
Q62711
772
88948
S746
Y
R
H
V
S
L
L
S
K
D
G
T
S
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
H713
S
L
K
M
G
Y
R
H
I
H
L
L
S
K
N
Chicken
Gallus gallus
Q2VRL0
637
72514
Y612
L
L
S
L
S
K
G
Y
C
T
V
P
L
F
S
Frog
Xenopus laevis
Q32NH8
758
87399
S731
Y
R
H
I
H
L
L
S
R
D
G
T
K
I
P
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
K750
Y
R
H
V
H
L
L
K
A
D
G
S
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
T788
Y
R
H
V
S
L
R
T
E
A
N
F
P
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
H728
S
M
Q
L
G
Y
H
H
V
P
I
L
G
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
I559
V
W
E
L
R
Q
G
I
R
A
V
P
L
R
N
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
A831
I
S
E
E
T
Q
I
A
S
V
C
L
K
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
73.3
N.A.
6.6
0
66.6
60
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
80
N.A.
20
6.6
80
73.3
N.A.
53.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% D
% Glu:
0
0
15
8
0
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
0
15
0
15
0
0
0
58
0
8
0
0
% G
% His:
0
0
65
0
43
0
8
15
0
8
0
0
0
0
15
% H
% Ile:
8
0
0
36
0
0
8
8
8
0
8
22
0
8
0
% I
% Lys:
0
0
8
0
0
8
0
8
36
0
0
0
15
8
8
% K
% Leu:
8
15
0
22
0
65
58
0
0
0
8
22
15
58
0
% L
% Met:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
29
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
15
8
0
8
% P
% Gln:
0
0
8
0
0
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
65
0
0
8
0
15
0
22
0
0
0
0
8
15
% R
% Ser:
15
8
8
0
29
0
0
50
8
0
0
8
50
0
22
% S
% Thr:
0
0
0
0
8
0
0
8
0
8
0
29
8
0
0
% T
% Val:
8
0
0
29
0
0
0
0
8
8
15
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
65
0
0
0
0
15
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _