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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
22.42
Human Site:
S614
Identified Species:
37.95
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S614
F
L
R
D
I
Q
S
S
F
H
P
E
K
P
I
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S614
F
L
R
D
I
Q
S
S
F
H
P
E
K
P
I
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S651
F
L
R
D
N
Q
S
S
F
H
P
E
R
P
I
Dog
Lupus familis
XP_536069
769
88595
S621
F
L
R
D
A
Q
S
S
F
H
P
E
R
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S659
F
L
R
D
T
Q
S
S
F
N
P
E
R
P
I
Rat
Rattus norvegicus
Q62711
772
88948
S624
F
L
R
D
T
Q
S
S
F
N
P
M
K
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
R594
F
L
R
D
P
A
S
R
F
D
P
R
D
P
S
Chicken
Gallus gallus
Q2VRL0
637
72514
S497
E
F
L
R
N
R
N
S
T
F
N
P
H
N
V
Frog
Xenopus laevis
Q32NH8
758
87399
N609
R
H
V
E
T
T
F
N
P
D
Q
P
Q
G
T
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
D628
C
D
P
K
S
D
F
D
P
E
N
T
G
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D671
F
M
R
R
A
D
K
D
F
D
P
F
A
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
P612
K
P
V
F
C
R
K
P
N
M
Q
F
N
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
V444
L
L
L
K
S
N
A
V
F
D
P
E
A
T
L
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
V703
G
S
F
K
S
G
Y
V
L
K
P
K
K
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
86.6
80
N.A.
80
73.3
N.A.
53.3
6.6
0
0
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
53.3
26.6
20
0
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
8
0
0
0
0
0
15
0
8
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
50
0
15
0
15
0
29
0
0
8
8
0
% D
% Glu:
8
0
0
8
0
0
0
0
0
8
0
43
0
0
0
% E
% Phe:
58
8
8
8
0
0
15
0
65
8
0
15
0
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
0
0
0
0
8
15
8
% G
% His:
0
8
0
0
0
0
0
0
0
29
0
0
8
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
29
% I
% Lys:
8
0
0
22
0
0
15
0
0
8
0
8
29
0
0
% K
% Leu:
8
58
15
0
0
0
0
0
8
0
0
0
0
8
22
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
0
15
8
8
8
8
15
15
0
8
8
0
% N
% Pro:
0
8
8
0
8
0
0
8
15
0
72
15
0
58
0
% P
% Gln:
0
0
0
0
0
43
0
0
0
0
15
0
8
0
0
% Q
% Arg:
8
0
58
15
0
15
0
8
0
0
0
8
22
0
0
% R
% Ser:
0
8
0
0
22
0
50
50
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
22
8
0
0
8
0
0
8
0
8
8
% T
% Val:
0
0
15
0
0
0
0
15
0
0
0
0
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _