KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
23.94
Human Site:
S522
Identified Species:
40.51
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S522
Y
H
F
Y
E
I
S
S
F
S
E
T
K
A
K
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S522
Y
H
F
Y
E
I
S
S
F
S
E
T
K
A
K
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S559
Y
H
F
Y
E
I
S
S
F
S
E
T
K
A
K
Dog
Lupus familis
XP_536069
769
88595
S529
Y
R
F
Y
E
T
S
S
F
S
E
T
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S567
Y
H
I
Y
D
I
S
S
F
S
E
S
K
A
K
Rat
Rattus norvegicus
Q62711
772
88948
S532
Y
H
I
Y
D
I
S
S
F
S
E
S
K
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
E505
Y
E
M
S
S
L
S
E
N
K
A
L
R
L
V
Chicken
Gallus gallus
Q2VRL0
637
72514
K417
L
K
A
Q
K
F
V
K
H
A
A
N
Q
F
V
Frog
Xenopus laevis
Q32NH8
758
87399
E518
Y
E
M
S
S
V
T
E
Y
K
A
R
K
L
V
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
L543
S
E
N
E
A
L
K
L
I
K
D
S
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
S579
N
I
A
H
N
M
S
S
F
A
E
S
A
G
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
A529
S
S
F
G
E
A
K
A
F
G
L
A
E
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
K364
Q
L
E
K
A
S
E
K
Y
A
K
Q
I
V
R
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
E617
A
H
C
F
S
L
N
E
R
K
V
E
Y
M
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
13.3
0
13.3
0
N.A.
26.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
26.6
20
33.3
20
N.A.
53.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
15
8
0
8
0
22
22
8
8
43
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
0
22
8
8
36
0
8
22
0
0
50
8
8
0
0
% E
% Phe:
0
0
36
8
0
8
0
0
58
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
0
8
8
0
% G
% His:
0
43
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
15
0
0
36
0
0
8
0
0
0
8
0
8
% I
% Lys:
0
8
0
8
8
0
15
15
0
29
8
0
50
8
50
% K
% Leu:
8
8
0
0
0
22
0
8
0
0
8
8
0
15
8
% L
% Met:
0
0
15
0
0
8
0
0
0
0
0
0
0
8
8
% M
% Asn:
8
0
8
0
8
0
8
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
8
8
0
8
% R
% Ser:
15
8
0
15
22
8
58
50
0
43
0
29
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
0
0
0
0
29
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
8
0
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
58
0
0
43
0
0
0
0
15
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _