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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
28.48
Human Site:
S255
Identified Species:
48.21
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S255
L
I
D
R
Y
E
P
S
D
S
G
K
L
R
H
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S255
L
I
D
R
Y
E
P
S
D
S
G
K
L
R
H
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S255
L
I
D
R
Y
E
P
S
D
S
G
K
L
R
H
Dog
Lupus familis
XP_536069
769
88595
S257
L
I
D
R
Y
E
P
S
E
S
G
K
L
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S255
L
I
D
R
Y
E
P
S
E
N
G
R
L
L
H
Rat
Rattus norvegicus
Q62711
772
88948
S255
L
I
D
R
Y
E
P
S
E
N
G
R
L
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S242
L
I
E
R
Y
E
P
S
E
T
A
K
E
A
K
Chicken
Gallus gallus
Q2VRL0
637
72514
M159
H
R
T
V
Y
Q
D
M
N
H
P
L
C
D
Y
Frog
Xenopus laevis
Q32NH8
758
87399
S255
L
I
A
R
Y
E
P
S
D
T
A
K
K
L
H
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
N278
L
I
Q
T
F
E
L
N
D
W
A
Q
K
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D284
I
I
N
D
Y
E
L
D
E
E
K
K
K
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
N264
N
I
E
E
Y
E
P
N
Q
E
F
R
D
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
D106
L
E
V
H
Q
D
M
D
A
P
L
S
H
Y
F
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
W345
Q
V
D
R
Q
T
A
W
S
Y
F
I
K
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
93.3
N.A.
73.3
66.6
N.A.
53.3
6.6
66.6
26.6
N.A.
26.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
73.3
26.6
73.3
46.6
N.A.
46.6
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
8
0
22
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
50
8
0
8
8
15
36
0
0
0
8
8
0
% D
% Glu:
0
8
15
8
0
79
0
0
36
15
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
15
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
43
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
8
0
0
8
0
43
% H
% Ile:
8
79
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
50
29
0
15
% K
% Leu:
72
0
0
0
0
0
15
0
0
0
8
8
43
22
8
% L
% Met:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
15
8
15
0
0
0
15
0
% N
% Pro:
0
0
0
0
0
0
65
0
0
8
8
0
0
0
0
% P
% Gln:
8
0
8
0
15
8
0
0
8
0
0
8
0
8
0
% Q
% Arg:
0
8
0
65
0
0
0
0
0
0
0
22
0
29
15
% R
% Ser:
0
0
0
0
0
0
0
58
8
29
0
8
0
0
0
% S
% Thr:
0
0
8
8
0
8
0
0
0
15
0
0
0
0
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
79
0
0
0
0
8
0
0
0
15
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _