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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
35.45
Human Site:
S216
Identified Species:
60
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S216
Q
E
L
F
E
S
F
S
A
D
G
Q
K
L
T
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S216
Q
E
L
F
E
S
F
S
A
D
G
Q
K
L
T
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S216
Q
E
L
F
E
S
F
S
A
D
G
Q
K
L
T
Dog
Lupus familis
XP_536069
769
88595
S218
Q
E
L
F
E
N
F
S
A
D
G
Q
K
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S216
E
E
I
F
E
D
F
S
S
D
K
Q
K
L
T
Rat
Rattus norvegicus
Q62711
772
88948
S216
E
E
L
F
E
N
F
S
S
D
K
Q
K
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
S206
I
F
Q
S
I
A
G
S
A
D
T
L
S
V
D
Chicken
Gallus gallus
Q2VRL0
637
72514
D123
I
L
K
Y
E
P
I
D
E
V
R
K
R
R
Q
Frog
Xenopus laevis
Q32NH8
758
87399
S216
L
K
I
F
Q
D
F
S
K
D
G
K
K
L
T
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S241
D
A
V
F
R
H
Y
S
G
N
G
C
V
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
T236
E
E
L
F
T
S
I
T
K
G
K
Q
D
F
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
S225
Q
E
V
F
K
K
Y
S
G
D
D
D
Y
W
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
S70
A
Q
D
I
V
N
A
S
S
S
L
L
H
R
N
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
V269
C
D
K
F
H
I
Y
V
S
T
G
Q
L
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
93.3
N.A.
66.6
73.3
N.A.
20
6.6
53.3
33.3
N.A.
33.3
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
33.3
26.6
80
53.3
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
36
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
8
8
0
0
15
0
8
0
65
8
8
8
0
8
% D
% Glu:
22
58
0
0
50
0
0
0
8
0
0
0
0
0
8
% E
% Phe:
0
8
0
79
0
0
50
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
8
0
15
8
50
0
0
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
15
0
15
8
8
8
15
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
15
0
8
8
0
0
15
0
22
15
50
0
0
% K
% Leu:
8
8
43
0
0
0
0
0
0
0
8
15
8
65
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
22
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
36
8
8
0
8
0
0
0
0
0
0
58
0
0
8
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
0
8
15
0
% R
% Ser:
0
0
0
8
0
29
0
79
29
8
0
0
8
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
8
8
0
0
0
65
% T
% Val:
0
0
15
0
8
0
0
8
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
8
0
0
22
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _