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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC3
All Species:
29.09
Human Site:
S374
Identified Species:
58.18
UniProt:
Q9BQ90
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ90
NP_476502.1
382
43088
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
H
Chimpanzee
Pan troglodytes
XP_518484
389
43846
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001090916
382
43096
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
H
Dog
Lupus familis
XP_865234
382
43067
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM9
382
43063
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
H
Rat
Rattus norvegicus
Q6AYI2
382
43090
S374
M
T
T
N
S
N
I
S
R
P
I
V
S
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508538
534
60712
A374
A
P
P
Q
P
G
P
A
H
K
H
R
P
L
E
Chicken
Gallus gallus
Q5ZJ37
371
40041
R363
D
T
Q
A
E
I
Y
R
D
C
I
V
S
L
I
Frog
Xenopus laevis
Q5U580
411
46740
S403
Q
L
L
Q
L
G
L
S
Q
E
L
I
E
R
L
Zebra Danio
Brachydanio rerio
NP_998434
226
25323
S219
Y
C
I
R
S
R
S
S
T
P
R
P
T
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122948
420
47508
Y400
A
D
I
R
F
E
M
Y
C
Q
V
M
P
N
V
Sea Urchin
Strong. purpuratus
XP_001189761
385
43853
T375
M
I
S
N
S
D
I
T
P
L
P
Y
E
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
99.7
97.9
N.A.
96.8
97.1
N.A.
59.9
23.2
20.6
48.6
N.A.
N.A.
N.A.
40.9
47
Protein Similarity:
100
97.6
100
98.6
N.A.
98.4
98.4
N.A.
64.6
39.2
36.7
54.4
N.A.
N.A.
N.A.
57.6
64.4
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
0
26.6
6.6
20
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
6.6
26.6
33.3
33.3
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
9
0
0
0
0
0
17
0
% A
% Cys:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
9
0
0
0
9
0
0
17
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
42
% H
% Ile:
0
9
17
0
0
9
59
0
0
0
59
9
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
9
9
0
9
0
9
0
0
9
9
0
0
17
9
% L
% Met:
59
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
59
0
50
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
9
9
0
9
0
9
0
9
59
9
9
17
0
9
% P
% Gln:
9
0
9
17
0
0
0
0
9
9
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
9
0
9
50
0
9
9
0
9
0
% R
% Ser:
0
0
9
0
67
0
9
67
0
0
0
0
59
50
0
% S
% Thr:
0
59
50
0
0
0
0
9
9
0
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
59
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _