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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC3
All Species:
4.55
Human Site:
S175
Identified Species:
9.09
UniProt:
Q9BQ90
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ90
NP_476502.1
382
43088
S175
T
L
I
C
T
K
G
S
P
A
R
W
R
D
F
Chimpanzee
Pan troglodytes
XP_518484
389
43846
N175
T
L
I
C
T
K
G
N
P
A
R
W
R
D
F
Rhesus Macaque
Macaca mulatta
XP_001090916
382
43096
N175
T
L
I
C
T
K
G
N
P
A
R
W
R
D
F
Dog
Lupus familis
XP_865234
382
43067
N175
T
L
I
C
T
K
G
N
P
A
R
W
R
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM9
382
43063
N175
T
L
V
C
T
K
G
N
P
A
R
W
R
D
F
Rat
Rattus norvegicus
Q6AYI2
382
43090
N175
T
L
V
C
T
K
G
N
P
A
R
W
R
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508538
534
60712
T175
T
L
I
S
A
K
G
T
P
A
R
W
R
D
F
Chicken
Gallus gallus
Q5ZJ37
371
40041
H184
A
W
T
Q
P
D
T
H
G
D
P
P
S
P
R
Frog
Xenopus laevis
Q5U580
411
46740
P221
I
Q
L
R
P
N
N
P
P
C
D
L
P
E
E
Zebra Danio
Brachydanio rerio
NP_998434
226
25323
T40
C
S
G
E
D
Y
E
T
L
R
Q
I
D
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001122948
420
47508
D191
R
E
M
H
T
K
N
D
P
P
R
W
R
D
F
Sea Urchin
Strong. purpuratus
XP_001189761
385
43853
Q174
T
L
L
D
P
R
K
Q
I
P
H
W
R
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
99.7
97.9
N.A.
96.8
97.1
N.A.
59.9
23.2
20.6
48.6
N.A.
N.A.
N.A.
40.9
47
Protein Similarity:
100
97.6
100
98.6
N.A.
98.4
98.4
N.A.
64.6
39.2
36.7
54.4
N.A.
N.A.
N.A.
57.6
64.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
86.6
N.A.
80
0
6.6
0
N.A.
N.A.
N.A.
53.3
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
0
20
13.3
N.A.
N.A.
N.A.
60
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
0
0
0
0
59
0
0
0
0
0
% A
% Cys:
9
0
0
50
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
9
0
9
0
9
9
0
9
75
0
% D
% Glu:
0
9
0
9
0
0
9
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% F
% Gly:
0
0
9
0
0
0
59
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
9
% H
% Ile:
9
0
42
0
0
0
0
0
9
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
67
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
17
0
0
0
0
0
9
0
0
9
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
17
42
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
25
0
0
9
75
17
9
9
9
9
0
% P
% Gln:
0
9
0
9
0
0
0
9
0
0
9
0
0
0
0
% Q
% Arg:
9
0
0
9
0
9
0
0
0
9
67
0
75
0
9
% R
% Ser:
0
9
0
9
0
0
0
9
0
0
0
0
9
0
0
% S
% Thr:
67
0
9
0
59
0
9
17
0
0
0
0
0
0
0
% T
% Val:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
75
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _