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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRWD1
All Species:
10.61
Human Site:
T227
Identified Species:
17.95
UniProt:
Q9BQ67
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ67
NP_113673.3
446
49419
T227
L
D
W
S
P
R
V
T
G
R
L
L
T
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113650
446
49405
P227
L
D
W
S
P
R
V
P
G
R
L
L
T
G
D
Dog
Lupus familis
XP_854878
440
48695
S221
L
D
W
S
P
R
V
S
G
R
L
L
T
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q810D6
446
49215
P227
L
D
W
S
P
R
V
P
G
R
L
L
T
G
D
Rat
Rattus norvegicus
Q5XI13
445
49150
P226
L
D
W
S
P
R
V
P
G
R
L
L
T
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9W7I5
425
47588
H192
W
N
P
N
L
S
G
H
L
L
S
A
S
D
D
Frog
Xenopus laevis
O93377
425
47550
N192
W
N
P
N
L
S
G
N
L
L
S
A
S
D
D
Zebra Danio
Brachydanio rerio
Q7ZTY4
426
47733
N192
W
N
P
N
L
S
G
N
L
L
S
A
S
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24572
430
48616
Y196
W
N
P
N
L
N
G
Y
L
L
S
A
S
D
D
Honey Bee
Apis mellifera
XP_001121876
431
48870
A211
S
T
E
I
G
M
L
A
S
G
D
C
K
G
N
Nematode Worm
Caenorhab. elegans
NP_498091
453
50593
T241
L
A
W
S
S
L
K
T
G
D
L
A
T
G
D
Sea Urchin
Strong. purpuratus
XP_786328
581
65430
P207
L
D
W
S
P
T
V
P
G
T
M
L
S
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136925
481
52996
V239
A
I
D
W
S
P
L
V
T
G
R
L
V
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04225
511
57243
T287
D
W
S
P
L
I
K
T
G
A
L
L
S
G
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
91.9
N.A.
91.4
92.1
N.A.
N.A.
23.3
23.5
23.3
N.A.
23
47.7
43.9
43
Protein Similarity:
100
N.A.
98.8
96.6
N.A.
97
96.8
N.A.
N.A.
40.1
40.3
39.6
N.A.
39.6
66.8
60.7
56.4
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
6.6
60
66.6
P-Site Similarity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
26.6
26.6
N.A.
26.6
20
60
80
Percent
Protein Identity:
N.A.
42.2
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
58.4
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
8
0
36
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
43
8
0
0
0
0
0
0
8
8
0
0
29
86
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
29
0
58
15
0
0
0
65
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
0
0
0
0
8
0
0
% K
% Leu:
50
0
0
0
36
8
15
0
29
29
50
58
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
29
0
29
0
8
0
15
0
0
0
0
0
0
8
% N
% Pro:
0
0
29
8
43
8
0
29
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
36
0
0
0
36
8
0
0
0
0
% R
% Ser:
8
0
8
50
15
22
0
8
8
0
29
0
43
8
0
% S
% Thr:
0
8
0
0
0
8
0
22
8
8
0
0
43
0
0
% T
% Val:
0
0
0
0
0
0
43
8
0
0
0
0
8
0
0
% V
% Trp:
29
8
50
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _