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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRWD1
All Species:
36.67
Human Site:
S270
Identified Species:
62.05
UniProt:
Q9BQ67
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQ67
NP_113673.3
446
49419
S270
S
V
E
D
L
Q
W
S
P
T
E
N
T
V
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113650
446
49405
S270
S
V
E
D
L
Q
W
S
P
T
E
N
T
V
F
Dog
Lupus familis
XP_854878
440
48695
S264
S
V
E
D
L
Q
W
S
P
T
E
D
T
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q810D6
446
49215
S270
S
V
E
D
L
Q
W
S
P
T
E
D
T
V
F
Rat
Rattus norvegicus
Q5XI13
445
49150
S269
S
V
E
D
L
Q
W
S
P
T
E
D
T
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9W7I5
425
47588
W235
A
V
V
E
D
V
S
W
H
L
L
H
E
S
L
Frog
Xenopus laevis
O93377
425
47550
W235
A
V
V
E
D
V
S
W
H
L
L
H
E
S
L
Zebra Danio
Brachydanio rerio
Q7ZTY4
426
47733
W235
A
V
V
E
D
V
S
W
H
L
L
H
E
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24572
430
48616
W239
A
V
V
E
D
V
A
W
H
L
L
H
E
S
L
Honey Bee
Apis mellifera
XP_001121876
431
48870
S254
S
V
E
D
I
Q
W
S
P
N
E
K
H
V
L
Nematode Worm
Caenorhab. elegans
NP_498091
453
50593
S284
S
V
E
D
L
A
W
S
P
T
E
T
G
L
L
Sea Urchin
Strong. purpuratus
XP_786328
581
65430
S406
S
V
E
D
I
Q
W
S
P
N
E
K
N
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001136925
481
52996
S282
S
V
E
D
L
Q
W
S
P
T
E
A
D
I
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04225
511
57243
S330
S
I
E
D
I
Q
W
S
R
T
E
S
T
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.9
91.9
N.A.
91.4
92.1
N.A.
N.A.
23.3
23.5
23.3
N.A.
23
47.7
43.9
43
Protein Similarity:
100
N.A.
98.8
96.6
N.A.
97
96.8
N.A.
N.A.
40.1
40.3
39.6
N.A.
39.6
66.8
60.7
56.4
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
66.6
66.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
26.6
26.6
26.6
N.A.
26.6
73.3
73.3
80
Percent
Protein Identity:
N.A.
42.2
N.A.
N.A.
33
N.A.
Protein Similarity:
N.A.
58.4
N.A.
N.A.
50.2
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
72
29
0
0
0
0
0
0
22
8
0
0
% D
% Glu:
0
0
72
29
0
0
0
0
0
0
72
0
29
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
29
0
0
29
8
0
0
% H
% Ile:
0
8
0
0
22
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% K
% Leu:
0
0
0
0
50
0
0
0
0
29
29
0
0
8
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
0
15
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
72
0
0
0
0
0
22
72
0
0
0
8
0
29
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
58
0
8
43
0
0
% T
% Val:
0
93
29
0
0
29
0
0
0
0
0
0
0
58
0
% V
% Trp:
0
0
0
0
0
0
72
29
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _